Results 41 to 50 of about 705,503 (291)

Association of dietary calcium intake, total and ionized serum calcium levels with preeclampsia in Ethiopia

BMC Pregnancy and Childbirth, 2021
Background Preeclampsia is a well-known cause of maternal mortality and morbidity in Ethiopia. The exact pathophysiology has not been fully understood.
Rahel D. Gebreyohannes, Ahmed Abdella, Wondimu Ayele, Ahizechukwu C. Eke   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Mortality or Dialysis Dependency at Day 60 –Recommended Ionized Calcium Range.

, 2015
Mortality or Dialysis Dependency at Day 60 –Recommended Ionized Calcium Range.
Claude M. Galphin (779822), Devasmita Dev (779827), James A. Tumlin (779821), J. Ricardo DaSilva (779828), Alexander S. Yevzlin (779829), H. David Humes (353181), Brad C. Astor (245400), Micah R. Chan (779823), Ashita J. Tolwani (706125), Anitha Vijayan (779824), Kevin Finkel (779825), Balazs Szamosfalvi (779826)   +11 more
core   +1 more source

Additional file 3 of Trauma-induced disturbances in ionized calcium levels correlate parabolically with coagulopathy, transfusion, and mortality: a multicentre cohort analysis from the TraumaRegister DGU®

, 2023
Additional file 3.
Sandra Verelst (16506406), Rolf Lefering (33022), Mark Fitzgerald (2404138), Carlo Missant (16506409), Dries Helsloot (16506403)   +4 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Correlates of incident hypocalcemia amongst trauma patients in the Western Cape of South Africa: a secondary analysis of the Epidemiology and Outcomes of Prolonged Trauma Care (EpiC) study

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Background Derangements in ionized calcium are common following trauma, with prior research describing an association between hypocalcemia and adverse outcomes such as mortality, coagulopathy severity, and transfusion requirement.
Jessica B. Oudakker, Christiaan A. Rees, George Oosthuizen, Elmin Steyn, Shaheem de Vries, Janette Verster, Craig Wylie, Mohammed Mayet, Lesley Hodsdon, Karlien Doubell, Leigh Wagner, L’Oreal Snyders, Denise Lourens, Julia M. Dixon, Jessica L. Wild, Mengli Xiao, Lani Finck, Steven G. Schauer, Hendrick J. Lategan, Nee-Kofi Mould-Millman   +19 more
doaj   +1 more source

Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease

Journal of Veterinary Internal Medicine, 2018
Background Hypercalcemia is commonly associated with chronic kidney disease (CKD) in cats. Objectives To explore the calcitonin response to naturally occurring ionized hypercalcemia in cats with azotemic CKD, and to assess the relationship of plasma ...
D.H.N. van den Broek, R.F. Geddes, T.L. Williams, Y.‐M. Chang, J. Elliott, R.E. Jepson   +5 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Relationship between ionized calcium and serum albumin level in children with idiopathic nephrotic syndrome

, 2016
Background Nephrotic syndrome (NS) patients frequently have abnormalities in calcium metabolism that manifest as hypocalcemia and reduced intestinal absorption of calcium.
Nanan Sekarwana, Dida Akhmad Gurnida, Viiola Irene Winata   +2 more
core   +1 more source