Results 61 to 70 of about 705,503 (291)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Changes in serum phosphate, total serum calcium, ionized calcium, potassium, magnesium, and BUN levels during the first two weeks of life.

, 2019
Changes in serum phosphate, total serum calcium, ionized calcium, potassium, magnesium, and BUN levels during the first two weeks of life.
Yun Sil Chang (7305641), Jin Hwa Choi (3841891), So Yoon Ahn (7305647), Yohan Ho (7305644), Jisook Kim (2681002), Se In Sung (7305638), Won Soon Park (7305650)   +6 more
core   +1 more source

Surface ionization of metastable calcium atoms

AIP Advances, 2021
We report on an experimental study of surface ionization of metastable calcium atoms on a hot polycrystalline tungsten surface in vacuum. We implemented a hollow-cathode discharge to excite a fraction of calcium atoms in an atomic beam to metastable ...
I. Bucay, A. Helal, M. G. Raizen
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Adjusted calcium concentration as a predictor of ionized hypocalcemia in hypoalbuminemic dogs

Journal of Veterinary Internal Medicine, 2021
Background Ionized calcium (iCa) is the biologically active fraction of total calcium (tCa) with clinical relevance to evaluate calcium homeostasis, but not all primary veterinarians have access to serum iCa.
Fiamma De Witte, Alan Klag, Peter Chapman   +2 more
doaj   +1 more source

Evaluation of Capillaries for Ionized Calcium Measurements [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1992
Commercially available capillaries containing calcium-titrated heparinate as an anticoagulant designed specifically for ionized calcium measurements in blood were tested with four serum pools with ionized calcium concentrations adjusted to 0·75, 1·25, 1·50 and 2·50 mmol/L.
C, Sachs, P, Rabouine, C, Kindermans, M D, Dautzenberg, M, Dechaux   +4 more
openaire   +2 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Is Cytosolic Ionized Calcium Regulating Neutrophil Activation?

, 1983
The concentration of cytosolic ionized calcium, [Ca2+]i, was measured in intact neutrophils by use of a fluorescent indicator trapped in the icytoplasm. A given rise of [Ca2+]i elicited by the chemotactic peptide formylmethionylleucylphenylalanine (FMLP)
Claes B. Wollheim, Lew, Daniel Pablo, Pozzan, T., Roger Y. Tsien, Daniel P. Lew, Wollheim, Claes, Tullio Pozzan, Tsien, R. Y.   +7 more
core   +1 more source

Severe Hypertriglyceridemia Without Pancreatitis Causing Total Pseudohypocalcemia With True Ionized Symptomatic Hypocalcemia: A Diagnostic Pitfall

Clinical Case Reports
Severe hypertriglyceridemia (HTG) can interfere with laboratory assays. HTG‐induced pancreatitis usually presents with hypocalcemia, but the effect of severe HTG, with no associated pancreatitis, on calcium levels is not well described.
Mohamed Abuelazm, Marwah Algodi, Ahmed W. Hageen, Bassam Al Haly, Asawer Alsaeedi, Abdelrahman Awad, Hatem Eltaly, Omar Saab   +7 more
doaj   +1 more source

On the Ionization of Calcium Citrate.

Experimental Biology and Medicine, 1927
The hypothesis that citrate ions combine with calcium ions in some way and thus remove them from solution serves to explain a number of observations. Among these may be mentioned the following: non-precipitation of calcium phosphate in alkaline solutions when magnesium citrate is present; the failure of Shipley, Kramer and Howland1 to obtain ...
M. J. Shear, B. Kramer
openaire   +1 more source