Results 41 to 50 of about 1,309,766 (306)

Two new ²²²Rn emanation sources – a comparison study [PDF]

Atmospheric Measurement Techniques
More than 50 % of naturally occurring radiation exposure to the general public is due to the noble gas radon (222Rn) and its progenies, causing considerable health risks.
T. J. Ballé, S. Röttger, F. Mertes, A. Honig, P. Kovar, P. P. S. Otáhal, A. Röttger   +6 more
doaj   +1 more source

Influence of ionizing radiation on human body [PDF]

, 2016
This article describes positive and negative aspects of ionizing radiation and its effects on human body. Being a part of various medical procedures in medicine, ionising radiation has become an important aspect for both medical practitioners and ...
Jonatan Nowakowski, Alina Szlagor, Zygmunt Zdrojewicz, Marta Wielogórska, Dorota Nowakowska   +4 more
core   +1 more source

Ionizing radiation effects on blood-derived extracellular vesicles: insights into miR-34a-5p-mediated cellular responses and biomarker potential

Cell Communication and Signaling
Adverse effects of ionizing radiation on normal tissues limit the radiation dose in cancer treatment, thereby compromising treatment efficiency. Among the consistently affected non-cancer cells, peripheral blood mononuclear cells (PBMCs) exhibit high ...
Chiara Huber, Omar Elsaeed, Pia Lahmer, Simone Moertl   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Ionizing Radiation and Life [PDF]

Astrobiology, 2011
Ionizing radiation is a ubiquitous feature of the Cosmos, from exogenous cosmic rays (CR) to the intrinsic mineral radioactivity of a habitable world, and its influences on the emergence and persistence of life are wide-ranging and profound. Much attention has already been focused on the deleterious effects of ionizing radiation on organisms and the ...
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Ionizing Radiation in Medical Imaging and Efforts in Dose Optimization [PDF]

, 2012
Medical-related radiation is the largest source of controllable radiation exposure to humans and it accounts for more than 95% of radiation exposure from man-made sources.
Carl A. Roobottom, Roobottom, CA, Carl A., Vardhanabhuti, V, Varut Vardhanabhuti   +4 more
core   +1 more source

Exploring Non-Genetic Factors in Cancer Resistance among Ramsar Residents: From Medical Geology to the Role of Diet: A Review [PDF]

International Journal of Nutrition Sciences
Ramsar in northern Iran provides a unique natural setting to investigate the biological effects of exposure to chronic radiation and the potential adaptive mechanisms. It is owing to its exceptional high concentrations of radium in sedimentary rocks, hot
Hassan Bahrami, Pouya Zohdparast, Hassan Vafapour, AmirAli Fallah, Seyed Mohammad Javad Mortazavi, Fateme Zaker, Maryam Arshadi, Alireza Mortazavi, Seyed Jalil Masoumi   +8 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source