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Ionophores

Veterinary Clinics of North America: Equine Practice
Ionophores are a class of polyether antibiotics that are commonly used as anticoccidial agents and growth promotants in ruminant diets. Ionophores transport ions across lipid membranes and down concentration gradients, which results in mitochondrial destruction, reduced cellular energy production, and ultimately cell death.
Scott A, Fritz, Jeffery O, Hall
openaire   +3 more sources

Chiral ionophores

Pure and Applied Chemistry, 1978
Abstract
openaire   +1 more source

Ionophore-Based Optical Sensors

Annual Review of Analytical Chemistry, 2014
This review provides an overview of the key aspects of designing ionophore-based optical sensors (IBOS). Exact response functions are developed and compared with a simplified, generalized equation. We also provide a brief introduction into less established but promising working principles, namely dynamic response and exhaustive exchange. Absorbance and
Mistlberger, Gunter   +2 more
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Ionophores

Journal of Chemical Education, 1979
Discovery, structure, and mechanism of ionophores, molecular complexes that pass through biological membranes.
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Is Avenaciolide Another Ionophore?

Nature New Biology, 1973
THE neutral dilactone, avenaciolide1, has been reported to block glutamate transport in mitochondria2 and has been used to obtain a measure of glutamate binding sites on the membrane3.
E J, Harris, J M, Wimhurst
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Conformationally switched-on polyether ionophores

Chirality, 1998
The syntheses of two types of conformationally switched podand ionophores and their ionophoric properties are described. Both feature cyclohexane rings with polyether groups as trans 1,2 substituents. In the “switched off” forms of the ionophores, the two podand substituents are constrained to a diaxial orientation and cannot chelate a metal ion.
Morton Raban   +4 more
openaire   +1 more source

Lysine-sandwiched ionophores

Tetrahedron Letters, 1993
Abstract Lysine-sandwiched ionophores, prepared from N α -Z-Lys-OMe by insertion of preformed Cu(II)/Ni(II) templates of 3-substituted salicylaldehydes, transport Li, Na, K, Cs, Ca and ammonium ions, across layers and model biological membranes. The Ca(II) transport profile of ionophores from higher members of the series is noteworthy.
Subramania Ranganathan   +1 more
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Ionophore Toxicity and Tolerance

Veterinary Clinics of North America: Food Animal Practice, 2011
The rapid growth of the biofuels industry in the Midwest in the past 10 years has created an increased supply of corn coproduct feed for animals. This article discusses the tolerance and toxicology of biofuels coproducts in ruminants, including polioencephalomalacia, sulfur toxicosis, sulfur metabolism, mycotoxins, antibiotic residue, and biodiesel by ...
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Novel Amphi-Ionophores

The Journal of Physical Chemistry B, 1998
The interactions of cyclic peptides containing glycines with cations (Li+, Na+, Be2+, Mg2+) and anions (F- and Cl-) have been investigated using ab initio calculations.
Kim, KS, Cui, CZ, Cho, SJ
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