Results 101 to 110 of about 33,342 (190)

Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management

MedComm, Volume 7, Issue 7, July 2026.
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu, Xinyan Wu, Ting Yin, Feining Huang, Manqi Kong, Yu Yang, Zinan Liu, Jiabin Yu, Tianpeng Zhang   +8 more
wiley   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists

British Journal of Pharmacology, Volume 183, Issue 14, Page 3935-3949, July 2026.
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley   +1 more source

Selected Ionotropic Receptors and Voltage-Gated Ion Channels: More Functional Competence for Human Induced Pluripotent Stem Cell (iPSC)-Derived Nociceptors. [PDF]

Brain Sci, 2020
Schoepf CL, Zeidler M, Spiecker L, Kern G, Lechner J, Kummer KK, Kress M.   +6 more
europepmc   +1 more source

Ionotropic receptors mediate arachidic acid perception and food avoidance behavior in Drosophila melanogaster. [PDF]

Mol Cells
Pradhan RN, Atif M, Lee Y.
europepmc   +1 more source

Alternative strategies based on transgenic Drosophila melanogaster for the functional characterization of insect Ionotropic Receptors. [PDF]

Biol Res
Crava CM, Walker WB, Cattaneo AM.
europepmc   +1 more source

Genome-Wide Identification and Evolutionary Analysis of <i>Ionotropic Receptors</i> Gene Family: Insights into Olfaction Ability Evolution and Antennal Expression Patterns in <i>Oratosquilla oratoria</i>. [PDF]

Animals (Basel)
Yang WQ, Ding G, Wang LL, Yin CJ, Wu HY, Zhang HB, Liu QN, Jiang SH, Tang BP, Wang G, Zhang DZ.   +10 more
europepmc   +1 more source

Chemogenetic activation of mammalian brain neurons expressing insect Ionotropic Receptors by systemic ligand precursor administration. [PDF]

Commun Biol
Iguchi Y, Fukabori R, Kato S, Takahashi K, Eifuku S, Maejima Y, Shimomura K, Mizuma H, Mawatari A, Doi H, Cui Y, Onoe H, Hikishima K, Osanai M, Nishijo T, Momiyama T, Benton R, Kobayashi K.   +17 more
europepmc   +1 more source

Ionotropic Receptors Mediate Drosophila Oviposition Preference through Sour Gustatory Receptor Neurons. [PDF]

Curr Biol, 2017
Chen Y, Amrein H.
europepmc   +1 more source

Honey Bee Parasitic Mite Contains the Sensilla-Rich Sensory Organ on the Foreleg Tarsus Expressing Ionotropic Receptors With Conserved Functions. [PDF]

Front Physiol, 2019
Lei J, Liu Q, Kadowaki T.
europepmc   +1 more source