Results 131 to 140 of about 4,244,479 (353)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

An inducible whole-cell biosensor for detection of formate ions [PDF]

Ten strains of the yeast Yarrowia lipolytica were constructed, the genomes of which contain the hrGFP gene under regulation of the formate dehydrogenase promoters.
Yuzbashev, T., Melkina, O. E., Cherenkova, A. A.   +2 more
core   +1 more source

STUDY OF RHEOLOGICAL CHARACTERISTICS OF ORIGINAL BASIS TIZOL GEL AND MEDICINAL COMPOSITIONS ON THIS BASIS IN MANUAL RECIPES

Разработка и регистрация лекарственных средств, 2019
Rheological characteristics of the original basis tizol gel and medicinal compositions on this basis were studied by method of viscosimetry, constructed and analyzed curves of viscosity and flow curves objects of research, calculated their mechanical ...
M. V. Makhotina, B. B. Sysuev, A. U. Petrov, I. V. Emelyanova   +3 more
doaj  

Modeling the conditions for obtaining nanostructures during ion-plasma processing taking into account the quantum-mechanical properties of electrode material

Авіаційно-космічна техніка та технологія
The subject matter of the article is the thermophysical and mechanical properties of surface layers of structural materials using a quantum-mechanical approach.
Yurii Shyrokyi, Iurii Sysoiev, Yevhen Fesenko   +2 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Ion Sensitive Organic Field Effect Transistors [PDF]

, 2011
Ion sensitive organic field-effect transistors (ISOFETs) with a metal–oxide–semiconductor field-effect transistor (MOSFET) architecture have been fabricated by using poly(3-hexylthiophene) (P3HT) and poly(methyl methacrylate) (PMMA) as the semiconductor ...
RITJAREONWATTU, SUPACHAI
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Secondary hyperalgesia: from phenomenology to underlying mechanisms

, 2015
Speaker at the COSY seminars of the Institute of Neuroscience (IONS) of the Université catholique de Louvain (UCL, Brussels, Belgium.
Speaker at the Institute of neuroscience (IoNS-COSY) seminars Universite' catholique de Louvain, van den Broeke, Emanuel   +1 more
core  

Oxidative mechanisms in the toxicity of metal ions.

Free Radical Biology & Medicine, 1995
S. Stohs, D. Bagchi
semanticscholar   +1 more source