Results 41 to 50 of about 405,317 (235)
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
PANCREATITA CRONICĂ - MANAGEMENTUL DIAGNOSTICO - CURATIV MODERN
Cercetarea prezintă rezultatele tratamentului chirurgical aplicat la 530 pacienți cu pancreatită cronică (PC) în perioa- da anilor 1990-2022. Intervențiile chirurgicale realizate au fost: pancreatojejunostomie pe ansa Roux(PJA), duodenpan- createctomie ...
Adrian HOTINEANU +2 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
What nanotech inventors need to know about trade secrets and the prior user rights defense
The America Invents Act (AIA) presents new challenges and strategy considerations for nanotechnology inventors and companies that seek to protect their intellectual property in the United States. Among the many notable changes, the AIA expands the “prior
Pham Chinh H., Garsson Ross Spencer
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Las redes convergentes o redes de multiservicio hacen referencia a la integración de los servicios de voz, datos y video sobre una sola red basada en IP como protocolo de nivel de red.
Ángela Marcela Mejía Fajardo
doaj
Telah dilakukan evaluasi status mutu air sungai Opak menggunakan metode biotilik yang mudah, sederhana dan tergolong murah untuk pemantauan dan pengawasan lingkungan. Penelitian dilakukan dengan pengujian kualitas air sungai Opak pada 6 titik menggunakan
Roni Ardyantoro +2 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
CR-LDP como protocolo de señalización en redes de conmutación de etiquetas multiprotocolo
En este artículo se reportan los eventos suscitados y resultados obtenidos al utilizar CR-LDP como posible protocolo de señalización en redes MPLS, con miras a la búsqueda de la tan anhelada garantía de QoS para aplicaciones deboradoras de ancho de banda.
Danilo López +2 more
doaj

