Results 41 to 50 of about 2,490,039 (260)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Voz sobre Protocolo de Internet, VoIP
Prisma Tecnológico, 2016 Voz sobre Protocolo de Internet es un nuevo sistema que permite la transmisión de voz en pequeños paquetes a través de una red IP. Esta tecnología presenta ventajas y desventajas, pero lo más sobresaliente de este sistema es la calidad de la voz que ...
Kristel Vega
doaj
DiffServ resource management in IP-based radio access networks [PDF]
, 2001 The increasing popularity of the Internet, the flexibility of IP, and the wide deployment of IP technologies, as well as the growth of mobile communications have driven the development of IP-based solutions for wireless networking. The introduction of IP-
Heijenk, Geert +3 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Promoting Progress with Fair Use [PDF]
, 2011 The Intellectual Property (IP) Clause provides that Congress has the power to promote the Progress of Science and useful Arts by securing for limited Times to Authors and Inventors the exclusive Right to their respective Writings and Discoveries.
Mitchell, Joshua N.
core +1 more source
Computing Optimal Experimental Designs via Interior Point Method [PDF]
, 2012 In this paper, we study optimal experimental design problems with a broad class of smooth convex optimality criteria, including the classical A-, D- and p th mean criterion.
Lu, Zhaosong, Pong, Ting Kei
core +2 more sources
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Fictitious Commodities: A Theory of Intellectual Property Inspired by Karl Polanyi’s “Great Transformation” [PDF]
, 2019 The puzzle this Article addresses is this: how can it be explained that intellectual property (IP) laws and IP rights (IPRs) have continuously grown in number and expanded in scope, territorial reach, and duration, while at the same time have been ...
Peukert, Alexander
core +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Glimepiride, a novel sulfonylurea, does not abolish myocardial protection afforded by either ischemic preconditioning or diazoxide [PDF]
, 2001 Background: The sulfonylurea glibenclamide (Glib) abolishes the cardioprotective effect of ischemic preconditioning (IP), presumably by inhibiting mitochondrial KATP channel opening in myocytes. Glimepiride (Glim) is a new sulfonylurea reported to affect
Baxter, G.F. +5 more
core