Results 71 to 80 of about 2,523,737 (315)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

An Efficient Method to Enhance IP Telephony Performance in IPV6 Networks [PDF]

open access: diamond, 2021
Mosleh M. Abualhaj   +3 more
openalex   +1 more source

Velocity profiles of interplanetary shocks [PDF]

open access: yes, 1983
The type 2 radio burst was identified as a shock propagating through solar corona. Radio emission from shocks travelling through the interplanetary (IP) medium was observed.
Cane, H. V.
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

POLÍTICA NACIONAL DE RESÍDUOS SÓLIDOS E SUA GESTÃO NOS MUNICÍPIOS DO LITORAL NORTE DO ESTADO DE SÃO PAULO

open access: yesRevista UniVap, 2019
Este artigo tem como objetivo a análise das políticas públicas voltadas ao sistema de coleta e destinação dos resíduos sólidos urbanos na região do Litoral Norte do Estado de São Paulo, composta pelos municípios de Caraguatatuba, Ilhabela, São Sebastião ...
Eliete Gianini de Oliveira   +2 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Resource management in IP-based radio access networks [PDF]

open access: yes, 2001
IP is being considered to be used in the Radio Access Network (RAN) of UMTS. It is of paramount importance to be able to provide good QoS guarantees to real time services in such an IP-based RAN.
El Allali, H., Heijenk, G.
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Consideraciones para la selección de sistemas de información contables y administrativos en la Pyme colombiana

open access: yesEntramado, 2008
En la selección de Sistemas de Información Contables y Administrativos para la PyME, se debe tener en cuenta tres aspectos básicos, el funcional, el técnico y la metodología de implementación, definidos de la siguiente manera: 1.El aspecto funcional, es ...
Marco Tulio Astudillo Cerón
doaj  

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