Results 41 to 50 of about 3,938,094 (293)
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Journal of Communications Software and Systems, 2006 In future wireless networks, Mobile IP will be widely deployed as a general mobility protocol. Currently, in theprotocol each mobile node (MN) should have one public home address to identify itself when it is away from home.
Zhen Zhen, Srinivas Sampalli
doaj
The Value of Geographic Locations Submitted by Internet Users
IEEE Access, 2018 Internet users may be asked to manually provide their contact details, including city or full postal address. Examples include use of trial/free applications and services, filling out on-line surveys and petitions, and membership registration to loyalty ...
Dan Komosny, Miralem Mehic
doaj +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Fast and Scalable IP Address Lookup with Time Complexity of LogmLogm(n)
Journal of Advances in Information Technology, 2014 Router is a device which is used to route the incoming data packets from the sender to the destination using the IP address of the destination side.
Abhishant Prakash, Alok Sagar Gautam
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FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Vectored-Bloom Filter for IP Address Lookup: Algorithm and Hardware Architectures
Applied Sciences, 2019 The Internet Protocol (IP) address lookup is one of the most challenging tasks for Internet routers, since it requires to perform packet forwarding at wire-speed for tens of millions of incomming packets per second. Efficient IP address lookup algorithms
Hayoung Byun, Qingling Li, Hyesook Lim
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Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source