Results 51 to 60 of about 5,870,276 (290)

Home Appliance Networking Using IPV6 Wireless Networks

open access: yesJournal of Engineering and Sustainable Development, 2013
This paper introduces a framework that adjusts electrical home appliances to meet the demanding needs of home networking, so that these appliances can be controlled through IP networks.
Rabab Jasim Muhsin
doaj  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

IP Address Allocation through the Lenses of Public Goods and Scarce Resources Theories

open access: yesSCRIPTed: A Journal of Law, Technology & Society, 2011
The current Internet Protocol (IP) addressing system, Internet Protocol version 4 (IPv4), is a resource with limitations. All IPv4 address blocks have now been allocated, posing a risk that not all IP address requests will be satisfied.
Rolf H. Weber, Ulrike I. Heinrich
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

IMPLEMENTASI STATIC NAT TERHADAP JARINGAN VLAN MENGGUNAKAN IP DYNAMIC HOST CONFIGURATION PROTOCOL (DHCP)

open access: yesJurnal Ilmiah Informatika, 2016
To build a network interconnect Local Area Network (LAN) that will be needed in the form of Virtual groups Local Area Network (LAN). DHCP IP address given by the router to the PC located in the network.
Juwanda Natali   +2 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Handover algorithm using fast DAD mechanism for hierarchical mobile IPv6

open access: yesTongxin xuebao, 2008
To solve the problem that the duplicate address detection (DAD) in hierarchical mobile IPv6 (HMIPv6) links too time consuming, a handover algorithm based on fast DAD mechanism for HMIPv6 was proposed.
CHEN Wei-xin   +3 more
doaj   +2 more sources

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