Results 51 to 60 of about 944,819 (280)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

A Multi-perspective Analysis of Carrier-Grade NAT Deployment

open access: yes, 2016
As ISPs face IPv4 address scarcity they increasingly turn to network address translation (NAT) to accommodate the address needs of their customers. Recently, ISPs have moved beyond employing NATs only directly at individual customers and instead begun ...
Allman, Mark   +8 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Vectored-Bloom Filter for IP Address Lookup: Algorithm and Hardware Architectures

open access: yesApplied Sciences, 2019
The Internet Protocol (IP) address lookup is one of the most challenging tasks for Internet routers, since it requires to perform packet forwarding at wire-speed for tens of millions of incomming packets per second. Efficient IP address lookup algorithms
Hayoung Byun, Qingling Li, Hyesook Lim
doaj   +1 more source

Use Vlsm (Variable Length Subnet Masking) Android Based Simulator For Administrative Support Network [PDF]

open access: yes, 2013
Administration o f networking IP addressing especially IP version 4 have a less using IP address for the limited. Through for the using by networking o f services base on TCP/IP addressing, however that can be used VLSM (Variable Length Subnet Masking ...
Aji, B. W. (Bimio)   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Tracing IP-spoofed packets in software defined network

open access: yesTongxin xuebao, 2018
IP packets back tracing is to find the source host hop by hop from the destination.The method found the forwarding path of target packets and source host by adding probe entry into flow tables on SDN switches and analyzing the effective back tracing ...
Songjie WEI   +3 more
doaj   +2 more sources

Towards a SDN-Based Integrated Architecture for Mitigating IP Spoofing Attack

open access: yesIEEE Access, 2018
Current Internet packet delivery only relies on packet's destination IP address and forwarding devices neglect the validation of packet's IP source address, it makes attackers can leverage this flaw to launch attacks with forged IP source address so as ...
Chaoqin Zhang   +6 more
doaj   +1 more source

PEMANFAATAN BIND9 DALAM PEMBUATAN DOMAIN PADA VIRTUAL HOST MENGGUNAKANLINUX [PDF]

open access: yes, 2018
Domain adalah nama unik yang diberikan untuk mengidentifikasi nama server di jaringan komputer ataupun internet. Nama domain berfungsi untuk mempermudah client di internet pada saat melakukan akses ke server, selain itu dipakai juga untuk mengingat nama ...
NASA SAFRINA
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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