Results 1 to 10 of about 6,337 (179)

MRI-Derived Pancreatic Fat Fraction Is Independently Associated with Intraductal Papillary Mucinous Neoplasms: A Case–Control Study [PDF]

Diagnostics
Introduction: Intraductal papillary mucinous neoplasms (IPMNs) are precursor lesions of pancreatic cancer. This study investigated the association between MRI-derived pancreatic fat fraction and IPMN.
Sedat Çiçek, Delyadil Karakaş Kılıç, Selman Çetin, Abdulvahap Hohluoğlu, Furkan Kırsoy, Jehat Kılıç, Abdullah Mubin Özercan, Mustafa Yıldırım, Mehmet Yalnız, İbrahim Halil Bahçecioğlu   +9 more
doaj   +2 more sources

Humoral Predictors of Malignancy in IPMN: A Review of the Literature [PDF]

International Journal of Molecular Sciences, 2021
Pancreatic cystic lesions are increasingly detected in cross-sectional imaging. Intraductal papillary mucinous neoplasm (IPMN) is a mucin-producing subtype of the pancreatic cyst lesions arising from the pancreatic duct system. IPMN is a potential precursor of pancreatic cancer.
Marcello Candelli, Antonio Gasbarrini, Veronica Ojetti   +2 more
exaly   +3 more sources

Intraductal Papillary Mucinous Neoplasm (IPMN) of the Pancreas: History, Myths, and Realities Between Past and Future [PDF]

Medical Sciences
Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is among the most clinically relevant and conceptually intricate precancerous lesions encountered in modern gastroenterology. First identified in the early 1980s as a “mucin-producing tumor,”
Riccardo Urgesi, Cristiano Pagnini, Maria Carla Di Paolo, Lorella Pallotta, Gianfranco Fanello, Pavlos Antypas, Elio Pietro Perrone, Giuseppe Villotti, Andrea D’Amico, Fernando De Angelis, Maria Giovanna Graziani   +10 more
doaj   +2 more sources

Tumor-Derived LAMB3 Drives Immunosuppressive LRRC15⁺ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development. [PDF]

Adv Sci (Weinh)
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Shi X, Liu H, Sun J, Liu X, Jv X, Chen L, Zhang Y, Zhang H, Xing X, Li R, Ke X, Wang J, Yin X, Liu B, Liu Q, Wang Y, Lu J, Liu S, Pang J, Cai Y, Dai M, Bai F, Wu H, Liang Z.   +23 more
europepmc   +2 more sources

Cardiovascular-Kidney-Metabolic Syndrome Severity and Risk of Pancreatic Cancer in a Large Prospective Cohort. [PDF]

Diabetes Metab Res Rev
ABSTRACT Aims Pancreatic cancer remains one of the most lethal malignancies due to late diagnosis and limited opportunities for prevention. Cardiovascular–kidney–metabolic (CKM) syndrome reflects the cumulative burden of metabolic, renal, and cardiovascular dysfunction, but its association with pancreatic cancer risk has not been well established.
Choi M, Heo SJ, Kwon YJ, Kang CM.
europepmc   +2 more sources

Update in the diagnosis of IPMN

Suizo, 2018
Hiroyuki MAGUCHI, Akio KATANUMA, Kuniyuki TAKAHASHI   +2 more
exaly   +3 more sources

Comparison of clinicopathologic characteristics and survival outcomes between invasive IPMN and invasive MCN: A population-based analysis

Frontiers in Oncology, 2022
BackgroundIntraductal papillary mucinous neoplasm (IPMN) and mucinous cystic neoplasm (MCN) are two main histological subtypes of pancreatic cystic neoplasms with rapidly increasing incidence recently.
Zhen Yang, Guangjun Shi
doaj   +1 more source

Case report: Treatment of intraductal papillary mucinous neoplasms located in middle-segment pancreas with end-to-end anastomosis reconstruction after laparoscopic central pancreatectomy surgery through a pigtail-tube-stent placement of the pancreatic duct

Frontiers in Surgery, 2022
Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is one type of pancreatic cystic neoplasm. IPMNs can be classified into three types: main duct-IPMN (MD-IPMN), branch duct-IPMN (BD-IPMN), and mixed type-IPMN (MT-IPMN).
Guohua Liu, Xiaoyu Tan, Jiaxing Li, Guohui Zhong, Jingwei Zhai, Mingyi Li   +5 more
doaj   +1 more source

MRI features of intraductal papillary mucinous neoplasm of the bile ducts, “The myth about the cyst”: A systematic review

European Journal of Radiology Open, 2023
Rationale and objectives: Intraductal papillary mucinous neoplasm of the bile ducts (IPMN-B) is a true pre-cancerous lesion, which shares common features with pancreatic IPMN (IPMN-P).
Matan Kraus, Eyal Klang, Shelly Soffer, Yael Inbar, Eli Konen, Tamer Sobeh, Sara Apter   +6 more
doaj   +1 more source

Deep sequencing of cancer-related genes revealed GNAS mutations to be associated with intraductal papillary mucinous neoplasms and its main pancreatic duct dilation. [PDF]

PLoS ONE, 2014
To clarify the genetic mutations associated with intraductal papillary mucinous neoplasms (IPMN) and IPMN-related pancreatic tumours, we conducted cancer-related gene profiling analyses using pure pancreatic juice and resected pancreatic tissues.Pure ...
Shinichi Takano, Mitsuharu Fukasawa, Shinya Maekawa, Makoto Kadokura, Mika Miura, Hiroko Shindo, Ei Takahashi, Tadashi Sato, Nobuyuki Enomoto   +8 more
doaj   +1 more source