Results 71 to 80 of about 8,677 (217)

Discontinuing Surveillance of Low‐Risk Branch‐Duct Intraductal Papillary Mucinous Neoplasms in Routine Practice: An External Application of the “Trivial” Criteria and the Resources it Would Release in Fourteen Health Systems

United European Gastroenterology Journal, Volume 14, Issue 8, October 2026.
ABSTRACT Background Surveillance of low‐risk branch‐duct intraductal papillary mucinous neoplasms is usually lifelong. Criteria to stop it after 5 years of stability in older patients have not been tested outside the center that devised them, nor has their economic value been measured.
Claudio Ricci, Vincenzo D'Ambra, Martina Casarotto, Laura Alberici, Carlo Ingaldi, Marco Fichera, Cristina Mosconi, Marina Migliori, Riccardo Casadei   +8 more
wiley   +1 more source

Gene Expression Profiling of Pancreatic Ductal Adenocarcinoma Arising From Intraductal Papillary Mucinous Neoplasms of the Pancreas

Cancer Medicine
Introduction Intraductal papillary mucinous neoplasms (IPMNs) are diverse premalignant tumors of the pancreas. They progress stepwise from adenoma to carcinoma and offer an opportunity for intervention prior to malignant transformation into pancreatic ...
William A. Ziaziaris, Christopher S. H. Lim, Loretta Sioson, Anthony J. Gill, Jaswinder S. Samra, Sumit Sahni, Anubhav Mittal   +6 more
doaj   +1 more source

Precursor Lesions of Pancreatic Cancer

Gut and Liver, 2008
This review article describes morphological aspects, gene abnormalities, and mucin expression profiles in precursor lesions such as pancreatic intraepithelial neoplasia (PanIN), intraductal papillary mucinous neoplasm (IPMN), and mucinous cystic neoplasm
doaj   +1 more source

Pancreatic Atrophy: A Narrative Review and Surgical Interpretation

Annals of Gastroenterological Surgery, Volume 10, Issue 5, Page 1419-1427, September 2026.
Pancreatic parenchymal atrophy pattern and intraoperative margin assessment guide surgical strategy. ABSTRACT Despite recent advances in multimodal management, pancreatic ductal adenocarcinoma remains a fatal malignancy. Early detection of indirect findings of pancreatic ductal adenocarcinoma is essential to improve treatment outcomes, drawing ...
Rika Fujino, Ken‐ichi Okada, Yohei Masugi, Eisuke Iwasaki, Masaki Mori   +4 more
wiley   +1 more source

Intraductal Papillary Mucinous Neoplasia (IPMN) [PDF]

, 2010
The diagnosis and treatment of intraductal papillary mucinous tumors (IPMN) of the pancreas has evolved over the last decade. IPMN is a disease of the ductal epithelium and represent a spectrum of disease, ranging from benign to malignant lesions, making
Bussom, Scott, Saif, Muhammad Wasif
core   +1 more source

Cardiovascular–Kidney–Metabolic Syndrome Severity and Risk of Pancreatic Cancer in a Large Prospective Cohort

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Aims Pancreatic cancer remains one of the most lethal malignancies due to late diagnosis and limited opportunities for prevention. Cardiovascular–kidney–metabolic (CKM) syndrome reflects the cumulative burden of metabolic, renal, and cardiovascular dysfunction, but its association with pancreatic cancer risk has not been well established.
Munseok Choi, Seok‐Jae Heo, Yu‐Jin Kwon, Chang Moo Kang   +3 more
wiley   +1 more source

Neutrophil to Lymphocyte Ratio is a Predictive Factor of Malignant Potential for Intraductal Papillary Mucinous Neoplasms of the pancreas

Biomarker Insights, 2019
Intraductal papillary mucinous neoplasms (IPMNs) are cystic neoplasms with the potential for progression to pancreatic cancer. Accurate prediction of the malignant potential is challenging and a proper treatment strategy has not been well established ...
Riki Ohno, Ryuichi Kawamoto, Mami Kanamoto, Jota Watanabe, Masahiko Fujii, Hiromi Ohtani, Masamitsu Harada, Teru Kumagi, Hideki Kawasaki   +8 more
doaj   +1 more source

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

iMetaOmics, Volume 3, Issue 3, September 2026.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie, Jingyuan Ye, Sheng Wang, Maoyun Liu, Fengsheng Dai, Mingzhen Bai, Yi Wang, Athena Savoji, Yu Wang, Phillip B. Hylemon, Huiping Zhou, Hui Li, Dewei Li   +12 more
wiley   +1 more source

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, Volume 13, Issue 45, 13 August 2026.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Pancreatitis Is Frequently Associated with Pancreatic Side-Branch Intraductal Mucinous Neoplasia (SB-IPMN)

, 2016
Background: Pancreatitis can be associated with main-pancreatic duct (MPD) IPMN. This is thought to be related to intermittent obstruction of the MPD with viscous mucin.
Shroff, Puneet, Jonnalagadda, Sreenivasa S., Azar, Riad R., Sikka, Sanjay, Maple, John, Ringold, Daniel A., Early, Dayna S., Edmundowicz, Steven A.   +7 more
core   +1 more source