Results 151 to 160 of about 2,090 (184)
Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits [PDF]
Melanopsin is expressed in distinct types of intrinsically photosensitive retinal ganglion cells (ipRGCs), which drive behaviors from circadian photoentrainment to contrast detection. A major unanswered question is how the same photopigment, melanopsin, influences such vastly different functions.
Lutz Birnbaumer, Tiffany M Schmidt
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Color Discrimination Experiments Using Metameric ipRGC Stimuli
Keita Hirai
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Divergent Projection Patterns of M1 ipRGC Subtypes [PDF]
Abstract In addition to its well‐known role in pattern vision, light influences a wide range of non‐image forming, subconscious visual behaviors including circadian photoentrainment, sleep, mood, learning, and the pupillary light reflex.
Jennifer Y Li, Tiffany M Schmidt
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Selective Amplification of ipRGC Signals Accounts for Interictal Photophobia in Migraine [PDF]
Abstract Second only to headache, photophobia is the most debilitating symptom reported by people with migraine. While the melanopsin-containing, intrinsically photosensitive retinal ganglion cells (ipRGCs) are thought to play a role, how cone and melanopsin signals are integrated in this pathway to produce visual discomfort is poorly ...
Eric A Kaiser +2 more
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Circadian rhythm, ipRGCs, and dopamine signalling in myopia
Graefe's Archive for Clinical and Experimental Ophthalmology, 2023Myopia, a common ophthalmic disorder, places a high economic burden on individuals and society. Genetic and environmental factors influence myopia progression; however, the underlying mechanisms remain unelucidated. This paper reviews recent advances in circadian rhythm, intrinsically photosensitive retinal ganglion cells (ipRGCs), and dopamine (DA ...
Licheng Li +5 more
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Circadian Behavioral Responses to Light and Optic Chiasm-Evoked Glutamatergic EPSCs in the Suprachiasmatic Nucleus of ipRGC Conditional vGlut2 Knock-Out Mice [PDF]
Intrinsically photosensitive retinal ganglion cells (ipRGCs) innervate the hypothalamic suprachiasmatic nucleus (SCN), a circadian oscillator that functions as a biological clock. ipRGCs use vesicular glutamate transporter 2 (vGlut2) to package glutamate
Patricia J Sollars +2 more
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