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iPSCs: On the Road to Reprogramming Aging
Trends in Molecular Medicine, 2016Aging is characterized by irreversible loss of physiological integrity, often accompanied by an organism's loss of function and increased vulnerability to death. Defects in the mechanisms preserving cellular homeostasis over time may give rise to accelerated aging.
Clara, Soria-Valles +1 more
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Nihon rinsho. Japanese journal of clinical medicine, 2019
In addition to the discovery that mature cells can be reprogrammed to become pluripotent stem cells(iPS cells), the technical innovations of big-data analyses as well as the cutting- edge technologies such as nuclear reprogramming technique and genome-editing system are emerging a big paradigm shift in the field of regenerative medicine and aging. This
Ikki, Sakuma, Tomoaki, Tanaka
openaire +1 more source
In addition to the discovery that mature cells can be reprogrammed to become pluripotent stem cells(iPS cells), the technical innovations of big-data analyses as well as the cutting- edge technologies such as nuclear reprogramming technique and genome-editing system are emerging a big paradigm shift in the field of regenerative medicine and aging. This
Ikki, Sakuma, Tomoaki, Tanaka
openaire +1 more source