Results 251 to 260 of about 116,955 (355)

Energy metabolism, adenosine, and glutamate signaling reprogramming by decanoic acid in Glut1 disorder syndrome

Epilepsia Open, EarlyView.
Abstract Glut1 deficiency syndrome (Glut1DS) leads to neurological and cognitive symptoms and is primarily treated using carbohydrate‐restricted ketogenic diets. However, a recent clinical trial of a less restrictive, non‐ketogenic, medium chain triglyceride (MCT) diet with a high decanoic acid content suggests efficacy in Glut1DS treatment.
Erwann Pain, Yatra Kapatel, Pankaj K. Singh, Katie Lloyd Jones, Jamuna Selvakumaran, Alberto Malerba, Walter Lucchesi, Tricia Rutherford, Christina A. Gurnett, Matthew C. Walker, Robin S. B. Williams   +10 more
wiley   +1 more source

Pathophysiology of androgen-associated endothelial cell dysfunction in phenotype A polycystic ovarian syndrome revealed by iPSCs modeling. [PDF]

Front Endocrinol (Lausanne)
Wu CE, Huang CC, Hsiao YJ, Hsu CL, Chen TH, Chen MJ, Ho HN.   +6 more
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

From Dish to Trial: Building Translational Models of ALS. [PDF]

Cells
Salamotas I, Stavropoulou De Lorenzo S, Stachtiari A, Taxiarchis A, Tsolaki M, Michailidou I, Preza E.   +6 more
europepmc   +1 more source

Measurements of neurite extension and nucleokinesis in an iPSC-derived model system following microtubule perturbation [PDF]

Muriel Sébastien, Alexandra Paquette, Lilian Ferotin, Adam G. Hendricks, Gary J. Brouhard   +4 more
openalex   +1 more source

Lead‐free inorganic halide perovskite‐based synaptic memory for next generation neuromorphic computing

InfoMat, EarlyView.
Lead‐free inorganic halide perovskites enable resistive switching synaptic devices capable of mimicking biological learning and multimodal information processing, offering a promising platform for next‐generation neuromorphic computing and artificial intelligence hardware. Abstract Inorganic halide perovskites (IHPs) have emerged as promising materials
Subhasish Chanda, Deepak Kumar, Iman Biswas, Manisha Sharma, Youngmin Lee, Sejoon Lee, Sanjeev Kumar Sharma, Aniruddha Mondal   +7 more
wiley   +1 more source

Rheostats, not switches: Nuclear receptor dosage tunes somatic-to-iPSC reprogramming. [PDF]

Stem Cell Reports
Chronis C.
europepmc   +1 more source

Deletion of RFX6, a Diabetes-Associated Gene, Impairs iPSC-Derived Islet Organoid Development and Survival, With No Impact on the Generation of PDX1+/NKX6.1+ Progenitors [PDF]

Noura Aldous, Ahmed K. Elsayed, Bushra Memon, Sadaf Ijaz, Sikander Hayat, Essam M. Abdelalim   +5 more
openalex   +1 more source

Deuteration‐functionalized self‐assembled monolayers for UV‐durable perovskite solar cells

InfoMat, EarlyView.
Modification with deuterophenyl groups has been demonstrated to be an effective strategy for the construction of SAMs. The impressive PCE of 26.34% is by far one of the highest values for PSCs with the carbazole‐based SAMs as HTLs. This UV resistance performance represents the highest level of performance reported to date for PSCs using SAMs as HTLs ...
Desheng Li, Junjie Zhao, Bitao Dong, Qunping Fan, Zedong Lin, Fan Wu, Xiangwen Guo, Bingsuo Zou, Yingguo Yang, Fei Zhang, Long Jiang, Wei Ma, Yuhang Liu, Kai Chen   +13 more
wiley   +1 more source

Engineering of induced pluripotent stem cells for the efficient development of non-alloreactive, hypoimmunogenic CD8αβ CAR-T cells. [PDF]

Front Immunol
Nianias A, Katsarou A, Prins HJ, Shahrabi A, van Velzen C, Henneman L, Ruiter R, Mutis T, Groen R, Themeli M.   +9 more
europepmc   +1 more source