Results 101 to 110 of about 9,313 (272)

Lactobacillus amylovorus inhibits the TLR4 inflammatory signaling triggered by enterotoxigenic Escherichia coli via modulation of the negative regulators and involvement of TLR2 in intestinal Caco-2 cells and pig explants. [PDF]

open access: yesPLoS ONE, 2014
Inflammation derived from pathogen infection involves the activation of toll-like receptor (TLR) signaling. Despite the established immunomodulatory activities of probiotics, studies relating the ability of such bacteria to inhibit the TLR signaling ...
Alberto Finamore   +5 more
doaj   +1 more source

Archaeological Damage Assessment in Conflict Zones: Integrating Satellite Imagery and Ground Surveys in Daraa, Syria

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT Satellite remote sensing is among the most significant modern methodologies supporting field archaeology. In addition to its efficiency in identifying archaeological sites, remote sensing offers a safe and cost‐effective approach in conflict zones.
Amal Al Kassem   +5 more
wiley   +1 more source

The mechanism of excessive intestinal inflammation in necrotizing enterocolitis: an immature innate immune response.

open access: yesPLoS ONE, 2011
Necrotizing enterocolitis (NEC) is a devastating neonatal intestinal inflammatory disease, occurring primarily in premature infants, causing significant morbidity and mortality.
Nanda Nanthakumar   +8 more
doaj   +1 more source

Protective effect of dexamethasone on 5-FU-induced oral mucositis in hamsters. [PDF]

open access: yesPLoS ONE, 2017
Oral mucositis (OM) is an important side effect of cancer treatment, characterized by ulcerative lesions in the mucosa of patients undergoing radiotherapy or chemotherapy, which has marked effects on patient quality of life and cancer therapy continuity.
Susana Barbosa Ribeiro   +8 more
doaj   +1 more source

TGF-β-induced IRAK-M expression in tumor-associated macrophages regulates lung tumor growth. [PDF]

open access: yesOncogene, 2011
Tumor-associated macrophages (TAMs) constitute a major component of the immune cell infiltrate observed in the tumor microenvironment (TME). Factors present in the TME, including tumor growth factor-β (TGF-β), allow tumors to circumvent host-mediated immune responses to promote tumor progression.
Standiford TJ   +5 more
europepmc   +4 more sources

Modulation of porcine intestinal epitheliocytes immunetranscriptome response by Lactobacillus jensenii TL2937 [PDF]

open access: yes, 2016
In order to evaluate probiotic strains applicable for the beneficial immunomodulation of the porcine gut (immunobiotics), we previously developed a porcine intestinal epitheliocyte cell line (PIE cells).
Albarracín, Leonardo Miguel   +14 more
core   +1 more source

The Layout and Size of an Early Pre‐Pottery Neolithic B Small Settlement Revealed by Geophysical Prospection at Harbetsuvan Tepesi in Southeastern Anatolia

open access: yesArchaeological Prospection, EarlyView.
ABSTRACT In Upper Mesopotamia, the transition from the Pre‐Pottery Neolithic A (PPNA) to Pre‐Pottery Neolithic B (PPNB) period, ca. 10 800–10 600 cal. BP, is marked by a series of changes in chipped stone industries, architectural forms, symbolic objects, regional distribution of settlements and long‐distance exchange networks among others.
Toshihiro Tada   +7 more
wiley   +1 more source

Mitochondrial DAMPs induce endotoxin tolerance in human monocytes: an observation in patients with myocardial infarction.

open access: yesPLoS ONE, 2014
Monocyte exposure to mitochondrial Danger Associated Molecular Patterns (DAMPs), including mitochondrial DNA (mtDNA), induces a transient state in which these cells are refractory to further endotoxin stimulation.
Irene Fernández-Ruiz   +16 more
doaj   +1 more source

Exposure to Occupational Inhalants and the Risk of Developing Rheumatoid Arthritis: A Systematic Review and Meta‐Analysis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint pain, swelling, and stiffness. Although smoking is a well‐established risk factor for RA, the role of occupational inhalants in RA development is less well recognized.
Qianwen Liu   +7 more
wiley   +1 more source

Flavonoids affect host-microbiota crosstalk through TLR modulation [PDF]

open access: yes, 2014
Interaction between host cells and microbes is known as crosstalk. Among other mechanisms, this takes place when certain molecules of the micro-organisms are recognized by the toll-like receptors (TLRs) in the body cells, mainly in the intestinal ...
Castell, Margarida   +3 more
core   +4 more sources

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