Results 261 to 270 of about 9,313 (272)

IRAK4 autophosphorylation functions as a molecular switch to regulate death domain assembly and Myddosome maturation

Taylor M, Srikanth N, Deliz-Aguirre R, Gola DK, Bilay M, Ziska E, Kelsall I, Kukathu Y.   +7 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Identification and characterization of murine IRAK-M

Biochemical and Biophysical Research Communications, 2002
Interleukin-1 receptor-associated-kinases (IRAKs) are signal transduction mediators of the Toll/IL-1 receptor family, which comprise several transmembrane proteins involved in host defense mechanisms. Today four different human IRAKs (hu-IRAK-1, hu-IRAK-2, hu-IRAK-M, hu-IRAK-4) and two murine IRAKs (mouse pelle like kinase (mPLK) and mu-IRAK-4) have ...
Olaf, Rosati, Michael U, Martin
openaire   +2 more sources

Association Between Gene Polymorphisms of IRAK-M and the Susceptibility of Sepsis

Inflammation, 2013
The aim of this study was to explore the association between the single-nucleotide polymorphisms of interleukin-1 receptor-associated kinase-M (IRAK-M) gene and the susceptibility of sepsis. The allele frequency and genotype distribution of IRAK-M gene polymorphisms were assessed in 118 controls and 82 sepsis patients by semiquantitative polymerase ...
Gao-Hong, Dong, Jian-Ping, Gong, Jin-Zheng, Li, Yu-Hong, Luo, Zhen-Dong, Li, Pei-Zhi, Li, Kun, He   +6 more
openaire   +2 more sources

MECHANISMS OF PIN1 REGULATION OF IRAK-M STABILITY IN TLR/IL-1R SIGNALING AND STRUCTURE DETERMINATION OF IRAK-M DEATH DOMAIN

2018
Asthma is a chronic inflammatory sickness of the airways caused by environmental and genetic factors. The mechanisms of activation of the innate immunity signaling pathways that cause asthma are not fully understood yet. This study investigated the novel targets for the development of new asthma therapeutics.
openaire   +2 more sources

Procyanidin dimer B2-mediated IRAK-M induction negatively regulates TLR4 signaling in macrophages

Biochemical and Biophysical Research Communications, 2013
Polyphenolic compounds have been found to possess a wide range of physiological activities that may contribute to their beneficial effects against inflammation-related diseases; however, the molecular mechanisms underlying this anti-inflammatory activity are not completely characterized, and many features remain to be elucidated.
Nak-Yun, Sung, Mi-So, Yang, Du-Sub, Song, Jae-Kyung, Kim, Jong-Heum, Park, Beom-Seok, Song, Sang-Hyun, Park, Ju-Woon, Lee, Hyun-Jin, Park, Jae-Hun, Kim, Eui-Baek, Byun, Eui-Hong, Byun   +11 more
openaire   +2 more sources

Identification, characterisation and preliminary functional analysis of IRAK-M in grass carp (Ctenopharyngodon idella)

Fish & Shellfish Immunology, 2019
Interleukin-1 receptor-associated kinase (IRAK) family members play important roles in myeloid differentiation primary response 88 (MyD88)-dependent toll-like receptor (TLR) signaling, the crucial innate immune pathway in vertebrates. In the present study, the IRAK family gene IRAK-M (also called IRAK3) from grass carp (Ctenopharyngodon idella) was ...
Pengfei, Chu, Libo, He, Denghui, Zhu, Liangming, Chen, Rong, Huang, Lanjie, Liao, Yongming, Li, Zuoyan, Zhu, Yaping, Wang   +8 more
openaire   +2 more sources

Association of interleukin-1 receptor-associated kinase M (IRAK-M) and inflammatory bowel diseases

Scandinavian Journal of Gastroenterology, 2007
Inflammatory bowel diseases (IBD) have a complex genetic background. The interleukin receptor associated kinase-M (IRAK-M) is a NF-kappaB-mediated, negative regulator of Toll-like receptor (TLR) signaling. A functional mutation in a negative regulator might induce impaired endotoxin tolerance and increased inflammatory responses.
Weersma, Rinse K., Oostenbrug, Liekele E., Nolte, Ilja M., Van der Steege, Gerrit, Oosterom, Elvira, van Dullemen, Hendrik M., Kleibeuker, Jan H., Dijkstra, Gerard   +7 more
openaire   +3 more sources

Enabling Alzheimer?s A? phagocytosis by targeting IRAK-M innate immunity

2015
Microglia interact with A? through toll-like receptors (TLRs)
openaire   +1 more source

The Role Of IRAK-M In Regulating Acute Lung Injury

A34. LUNG INJURY: MECHANISM AND INTERVENTIONS, 2010
Megan N. Ballinger, Urvashi Bhan, Michael W. Newstead, Kenneth Lyn-Kew, Theodore J. Standiford   +4 more
openaire   +1 more source

IRAK-M Is Critical for Protection Against Hyperoxia-Induced Lung Injury.

B64. CELLULAR AND MOLECULAR ASPECTS OF ACUTE LUNG INJURY, 2009
KE Lyn-Kew, U Bhan, M Newstead, X Zeng, TJ Standiford   +4 more
openaire   +1 more source