Results 11 to 20 of about 117,100 (276)
Gastric LTi cells promote lymphoid follicle formation but are limited by IRAK-M and do not alter microbial growth. [PDF]
, 2015 Lymphoid tissue inducer (LTi) cells are activated by accessory cell IL-23, and promote lymphoid tissue genesis and antibacterial peptide production by the mucosal epithelium.
Banerjee, A +9 more
core +2 more sources
TLR9 activation induces normal neutrophil responses in a child with IRAK-4 deficiency: involvement of the direct PI3K pathway. [PDF]
, 2007 International audiencePolymorphonuclear neutrophils (PMN) play a key role in innate immunity. Their activation and survival are tightly regulated by microbial products via pattern recognition receptors such as TLRs, which mediate recruitment of the IL-1R-
El Benna, Jamel +11 more
core +3 more sources
USE OF GENETIC ALGORITHMS IN CREATING OIL BLENDS REQUIRED FOR REFINERY DISTILLATION PLAN [PDF]
Romanian Journal of Petroleum & Gas Technology, 2022 In Romania, the oil refineries were designed to process the crude oil extracted from the deposits located in their immediate vicinity (Suplacu de Barcău Refinery, 1 Mai Refinery, Câmpina Refinery, Vega Refinery and Dărmănești Refinery), to process crude ...
Reem Sabah Mohammed +3 more
doaj +1 more source
Innate Immunity, 2021 TLRs recognizing PAMPS play a role in local immunity and participate in implant-associated loosening. TLR-mediated signaling is primarily regulated by IL-1 receptor associated kinase-M (IRAK-M) negatively and IRAK-4 positively.
Yang-chun Zhang +3 more
doaj +1 more source
Türkçe ve Arapçada Ettirgen Çatısı
گۆڤارا زانستێن مرۆڤایەتی یا زانكۆیا زاخۆ, 2020 Türkçe ve Arapçada ettirgen çatısı başlıklı araştırmamız, fiilin aldığı bazı eklerle yeni bir kalıba ve duruma geçmesi dolayısıyla yeni bir fonksiyon ve yeni anlamlar ifade ettiğini göstermektedir. Nitekim fiile eklenen her ekin ya da harfin o fiili yeni
Faik Abbas
doaj +1 more source
ARTS: Artuklu Sanat ve Beşeri Bilimler Dergisi, 2022 Sosyal medya kullanımı son dönemlerde dünya çapında yaygın hale gelmiştir. Bireylerin çeşitli amaçlar ile kullandığı sosyal medya siyasi alanda da partilerin, liderlerin, seçimlerde adayların propagandalarını yapmak, vaatler ...
Hakan Irak
doaj +1 more source
Optineurin functions for optimal immunity [PDF]
, 2018 Optineurin (OPTN) was identified 20 years ago in a yeast-two-hybrid screen with a viral protein known to inhibit the cytolytic effects of tumor necrosis factor.
Slowicka, Karolina, van Loo, Geert
core +1 more source
Molecular genetics of renal cell carcinoma: polybromo 1 and set domain containing 2 genes
Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2016 Purpose: Renal cell carcinoma (RCC) is genetically characterized by the recurrent loss of the short arm of chromosome 3. Classically, Von Hippel Lindau (VHL) was the only frequently mutated gene in RCC.
Nadhum Jalal Ismaiel +2 more
doaj +1 more source
Interleukin-1 receptor-associated kinase 2- and protein kinase D1-dependent regulation of IRAK-monocyte expression by CpG DNA. [PDF]
PLoS ONE, 2012 As a part of the negative feedback mechanism, CpG DNA induces IRAK-M expression in monocytic cells. In the present study we investigated a biochemical signaling pathway and the transcription factors responsible for CpG DNA-mediated Irak-m gene expression.
Young-In Kim +4 more
doaj +1 more source
Emerging targets in human lymphoma: targeting the MYD88 mutation [PDF]
, 2016 B cell neoplasms co-opt the molecular machinery of normal B cells for their survival. Technological advances in cancer genomics has significantly contributed to uncovering the root cause of aggressive lymphomas, revealing a previously unknown link ...
Horikawa, Keisuke +2 more
core +1 more source