Results 11 to 20 of about 30,197 (254)

The IRAK-M death domain: a tale of three surfaces

Frontiers in Molecular Biosciences
The anti-inflammatory interleukin-1 receptor associated kinase-M (IRAK-M) is a negative regulator of MyD88/IRAK-4/IRAK-1 signaling. However, IRAK-M has also been reported to activate NF-κB through the MyD88/IRAK-4/IRAK-M myddosome in a MEKK-3 dependent ...
Berke Gürkan, Berke Gürkan, Hessel Poelman, Hessel Poelman, Liza Pereverzeva, Liza Pereverzeva, Danielle Kruijswijk, Danielle Kruijswijk, Alex F. de Vos, Alex F. de Vos, Anouk G. Groenen, Anouk G. Groenen, Edgar E. Nollet, Edgar E. Nollet, Kanin Wichapong, Esther Lutgens, Tom van der Poll, Tom van der Poll, Tom van der Poll, Jiangfeng Du, W. Joost Wiersinga, W. Joost Wiersinga, W. Joost Wiersinga, Gerry A. F. Nicolaes, Gerry A. F. Nicolaes, Cornelis van ‘t Veer, Cornelis van ‘t Veer   +26 more
doaj   +2 more sources

Effects of Excessive Violent Video Gaming on Memory and Its Brain Functions

, 2023
Two issues were reviewed in this chapter. First, the relationships between excessive violent video games (v-EVGP) and aggression and, second, the effects of v-EVGP on memory and its brain functions were discussed.
Irak, Metehan
core   +1 more source

Role of IRAK-M in Alcohol Induced Liver Injury [PDF]

, 2013
Increasing evidence suggests that innate immunity plays an important role in alcohol-induced liver injury and most studies have focused on positive regulation of innate immunity.
Flavell, R.A., Yan, H., Hu, Y., Yuksel, M., Colle, I., Wang, Y., Wen, L., Ma, Y., Chao, C.   +8 more
core   +1 more source

Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages [PDF]

, 2009
Background Toll-like receptors (TLRs) are present on monocytes and alveolar macrophages that form the first line of defense against inhaled particles.
Esmaeil Mortaz, Nijkamp, Frans P, Caldenhoven Eric, Caldenhoven, Eric, Kraneveld, Aletta D, Gert Folkerts, Sarir Hadi, Folkerts Gert, Nijkamp Frans P, Khalil Karimi, Kraneveld Aletta D, Karimi Khalil, Sarir, Hadi, Mortaz Esmaeil, Karimi, Khalil, Rahman Irfan, Folkerts, Gert, Frans P Nijkamp, Rahman, Irfan, Irfan Rahman, Eric Caldenhoven, Aletta D Kraneveld, Mortaz, Esmaeil, Hadi Sarir   +23 more
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Siyasal İletişimin Dijitalleşmesi: 2018 Cumhurbaşkanlığı Seçiminde Siyasal Partilerin Twitter Üzerinden Karşılaştırmalı Analizi

ARTS: Artuklu Sanat ve Beşeri Bilimler Dergisi, 2022
Sosyal medya kullanımı son dönemlerde dünya çapında yaygın hale gelmiştir. Bireylerin çeşitli amaçlar ile kullandığı sosyal medya siyasi alanda da partilerin, liderlerin, seçimlerde adayların propagandalarını yapmak, vaatler ...
Hakan Irak
doaj   +1 more source

Interleukin-1 receptor-associated kinase 2- and protein kinase D1-dependent regulation of IRAK-monocyte expression by CpG DNA. [PDF]

PLoS ONE, 2012
As a part of the negative feedback mechanism, CpG DNA induces IRAK-M expression in monocytic cells. In the present study we investigated a biochemical signaling pathway and the transcription factors responsible for CpG DNA-mediated Irak-m gene expression.
Young-In Kim, Jeoung-Eun Park, Ki Han Kwon, Cheol Yi Hong, Ae-Kyung Yi   +4 more
doaj   +1 more source

Changes in plasma IRAK-M in patients with prediabetes and its relationship with related metabolic indexes: a cross-sectional study

Journal of International Medical Research, 2022
Objective To investigate whether IL-1R-associated kinase (IRAK)-M is associated with prediabetes and type 2 diabetes (T2D). Methods In this cross-sectional study, enrolled subjects were assigned to different groups according to their fasting plasma ...
Xiaomin Xie, Guirong Bai, Li Zhang, Huili Liu, Dan Qiang, Ling Li   +5 more
doaj   +1 more source

Influence of plant growth regulators and sucrose on micropropagation of potato (Solanum tuberosum) cv. Burin

Acta Biológica Colombiana
A study was conducted to evaluate the effects of plant growth regulators, specifically benzyladenine (BAP) and kinetin (KIN), in combination with auxins (IAA and NAA), on the micropropagation of potato (Solanum tuberosum L.) cv. Burin.
Ahmed Mahmood Ibrahim, Mohammed D. Abdulhadi, Naeem A. Mutlag   +2 more
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IRAK-M suppresses the activation of microglial NLRP3 inflammasome and GSDMD-mediated pyroptosis through inhibiting IRAK1 phosphorylation during experimental autoimmune encephalomyelitis

Cell Death and Disease, 2023
The activation of the NOD-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome triggers pyroptosis proinflammatory cell death in experimental autoimmune encephalomyelitis (EAE).
Yuanyuan Wang, Shanshan Pei, Zhuhe Liu, Yuewen Ding, Tinglin Qian, Haixia Wen, Ssu-Wei Hsu, Zheyi Zhou, Jun Zhang, Honghao Wang   +9 more
doaj   +1 more source

Rutting performance of asphalt mixtures containing treated RCA and reinforced by carbon fibers

AiBi Revista de Investigación, Administración e Ingeniería
This study examined the rutting performance of hot asphalt mixtures containing treated RCA and reinforced by carbon fibers. The methodology involved substituting RCA instead of coarse virgin aggregates in the several percentages (20, 40, 60, 80, and 100%
Nadheer Albayati, Mohammed Qadir-Ismael
doaj   +1 more source