Results 31 to 40 of about 492,305 (300)

Encircling the regions of the pharmacogenomic landscape that determine drug response

open access: yesGenome Medicine, 2019
Background The integration of large-scale drug sensitivity screens and genome-wide experiments is changing the field of pharmacogenomics, revealing molecular determinants of drug response without the need for previous knowledge about drug action.
Adrià Fernández-Torras   +2 more
doaj   +1 more source

La empatía médica, ¿nace o se hace? Evolución de la empatía en estudiantes de medicina

open access: yesAtención Primaria, 2016
Introducción y objetivos: La empatía es una de las competencias básicas en el aprendizaje de la medicina, relacionándose con mejor relación médico-paciente, mejor competencia profesional y menor estrés profesional.
Montse Esquerda   +3 more
doaj   +1 more source

RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation

open access: yesEMBO Molecular Medicine, 2014
In estrogen receptor‐negative breast cancer patients, metastatic relapse usually occurs in the lung and is responsible for the fatal outcome of the disease. Thus, a better understanding of the biology of metastasis is needed. In particular, biomarkers to
Mònica Morales   +12 more
doaj   +1 more source

How Do Cancer-Related Mutations Affect the Oligomerisation State of the p53 Tetramerisation Domain?

open access: yesCurrent Issues in Molecular Biology, 2023
Tumour suppressor p53 plays a key role in the development of cancer and has therefore been widely studied in recent decades. While it is well known that p53 is biologically active as a tetramer, the tetramerisation mechanism is still not completely ...
Federica Nicolini   +7 more
doaj   +1 more source

What Is an IRB, Why Do We Need It, and What Is a Private IRB?

open access: yes, 2010
Many foot and ankle specialists have interest in publishing research or technique articles to share their expertise with colleagues. It is now commonplace for medical journals to require all studies that involve patients or patient data to have ...
Hyer, Christopher F
core   +1 more source

Integrating and formatting biomedical data as pre-calculated knowledge graph embeddings in the Bioteque

open access: yesNature Communications, 2022
Biomedical data is accumulating at a fast pace and integrating it into a unified framework is a major challenge. Here, the authors present a resource that contains pre-calculated biomedical descriptors derived from a very large knowledge graph.
Adrià Fernández-Torras   +4 more
doaj   +1 more source

Electronic IRB Submission with Cayuse IRB [PDF]

open access: yes, 2020
The purpose of the session will be to introduce and demo Cayuse IRB. On January 2, 2020, the IRB submission process at LU will change drastically when Cayuse IRB goes live!
Beltz, Cortney, Baker, Grace Michele
core   +1 more source

Microtubule nucleation and γTuRC centrosome localization in interphase cells require ch-TOG

open access: yesNature Communications, 2023
The molecular mechanisms underpinning the organization of microtubule arrays remain unclear. Here the authors show that in human cells, the microtubule polymerase ch-TOG promotes nucleation of microtubules at the interphase centrosome and the Golgi ...
Aamir Ali   +3 more
doaj   +1 more source

IRB Accreditation and Local IRB Operations

open access: yes, 2009
As presented at IASSIST 2009 ...
Elizabeth Stephenson   +2 more
openaire   +3 more sources

How local IRBs view central IRBs in the US [PDF]

open access: yesBMC Medical Ethics, 2011
Background: Centralization of IRB reviews have been increasing in the US and elsewhere, but many questions about it remain. In the US, a few centralized IRBs (CIRBs) have been established, but how they do and could operate remain unclear. Methods: I contacted 60 IRBs (every fourth one in the list of the top 240 institutions by NIH funding), and ...
openaire   +4 more sources

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