Results 21 to 30 of about 492,305 (300)

Ethics Governance Outside the Box: Reimagining Blockchain as a Policy Tool to Facilitate Single Ethics Review and Data Sharing for the 'omics' Sciences

Blockchain in Healthcare Today, 2018
Clinical research and health information data sharing are but ripples in a growing wave of reimagined applications of distributed ledger technologies beyond the digital marketplace for which they were originally created.
Vaso Rahimzadeh
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Ethics in academic research and scholarship: An elucidation of the principles and applications

Journal of Global Education and Research, 2019
Responsible, respectable, and successful engagement in research and scholarship in academia requires adherence to certain basic professional ethical principles to sustain the fidelity of academic work and the integrity of the researcher-scholar.
Olajide Agunloye
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Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway

Nature Communications, 2023
p38α is a versatile protein kinase that can control numerous processes and plays important roles in the cellular responses to stress. Dysregulation of p38α signaling has been linked to several diseases including inflammation, immune disorders and cancer,
Lorena González, Lucía Díaz, Joan Pous, Blazej Baginski, Anna Duran-Corbera, Margherita Scarpa, Isabelle Brun-Heath, Ana Igea, Pau Martin-Malpartida, Lidia Ruiz, Chiara Pallara, Mauricio Esguerra, Francesco Colizzi, Cristina Mayor-Ruiz, Ricardo M. Biondi, Robert Soliva, Maria J. Macias, Modesto Orozco, Angel R. Nebreda   +18 more
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IRB-approved TUTT protocol version 4.0_10 March 2020_.

, 2023
IRB-approved TUTT protocol version 4.0_10 March 2020_.
Limakatso Lebina (554886), Leisha P. Genade (15810802), Harry Hausler (3214485), Nina von Knorring (334027), Pren Naidoo (606701), Lucy Connell (15810811), Rebecca H. Berhanu (15338648), Neil A. Martinson (8587299), Helena Vreede (15810817), Anthony Kinghorn (5549672), Sipho Nyathi (15810808), Katherine Young (526710), Zameer Brey (15810805), Bareng A. S. Nonyane (8661561), Lawrence H. Moulton (7871810), Khine Swe Swe-Han (6596060), Mohamed Said (3588056), Keeren Lutchminarain (15810814)   +17 more
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The ATM signaling network in development and disease

Frontiers in Genetics, 2013
The DNA damage response (DDR) rapidly recognizes DNA lesions and initiates the appropriate cellular programs to maintain genome integrity. This includes the coordination of cell cycle checkpoints, transcription, translation, DNA repair, metabolism and ...
Travis H. Stracker, Ignasi eRoig, Philip A Knobel, Marko eMarjanovic, Marko eMarjanovic   +4 more
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Comparative analyses of vertebrate CPEB proteins define two subfamilies with coordinated yet distinct functions in post-transcriptional gene regulation

Genome Biology, 2022
Background Vertebrate CPEB proteins bind mRNAs at cytoplasmic polyadenylation elements (CPEs) in their 3′ UTRs, leading to cytoplasmic changes in their poly(A) tail lengths; this can promote translational repression or activation of the mRNA.
Berta Duran-Arqué, Manuel Cañete, Chiara Lara Castellazzi, Anna Bartomeu, Anna Ferrer-Caelles, Oscar Reina, Adrià Caballé, Marina Gay, Gianluca Arauz-Garofalo, Eulalia Belloc, Raúl Mendez   +10 more
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Exploring the OncoGenomic Landscape of cancer

Genome Medicine, 2018
Background The widespread incorporation of next-generation sequencing into clinical oncology has yielded an unprecedented amount of molecular data from thousands of patients.
Lidia Mateo, Oriol Guitart-Pla, Miquel Duran-Frigola, Patrick Aloy   +3 more
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Deleterious effects of neuronal accumulation of glycogen in flies and mice

EMBO Molecular Medicine, 2012
Under physiological conditions, most neurons keep glycogen synthase (GS) in an inactive form and do not show detectable levels of glycogen. Nevertheless, aberrant glycogen accumulation in neurons is a hallmark of patients suffering from Lafora disease or
Jordi Duran, María Florencia Tevy, Mar Garcia‐Rocha, Joaquim Calbó, Marco Milán, Joan J. Guinovart   +5 more
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Inhibition of p38 MAPK sensitizes tumour cells to cisplatin‐induced apoptosis mediated by reactive oxygen species and JNK

EMBO Molecular Medicine, 2013
The p38 MAPK pathway is an important regulator of many cellular responses. It is well established that p38 MAPK signalling negatively regulates epithelial cell transformation, but enhanced p38 MAPK activity has been also correlated with bad clinical ...
Lorena Pereira, Ana Igea, Begoña Canovas, Ignacio Dolado, Angel R. Nebreda   +4 more
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UNO IRB Submissions 2012-2016 [PDF]

, 2016
UNO IRB Submissions 2012 ...
IRB Office,
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