Results 1 to 10 of about 459,568 (307)
Academic Medicine, 2004 Improving medical practice begins with the improvement of medical education. In this process, most academic medical faculty assume the dual roles of both teacher and researcher, often without intending to or realizing that they are. With the increased tightening of regulation and supervision of biomedical research in the United States, academic medical
John M, Tomkowiak, Anne J, Gunderson
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American Journal of Clinical Pathology, 2001 During the last 2 years, regulatory agencies have taken a more visible role in the enforcement of statutory regulations that exist to protect the rights of human research subjects. In 1998 the Office of the Inspector General (OIG) of the Department of Health and Human Services (DHHS) issued a series of reports addressing inadequacies in the ...
C M, Lehman, G M, Rodgers
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Bioactivity descriptors for uncharacterized chemical compounds
Nature Communications, 2021 Chemical descriptors encode the physicochemical and structural properties of small molecules, and they are at the core of chemoinformatics. The broad release of bioactivity data has prompted enriched representations of compounds, reaching beyond chemical
Martino Bertoni +12 more
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IRB Reform in North America: Challenges and Opportunities
McGill Journal of Medicine, 2020 Clinical research is necessary to advance medical knowledge and to test new drugs or devices. It is therefore vital to society, and ethically imperative, that clinical studies be performed if patients are to have access to safe and effective treatments ...
Marjorie Ellen Zettler
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Increasing the precision of orthology-based complex prediction through network alignment [PDF]
PeerJ, 2014 Macromolecular assemblies play an important role in almost all cellular processes. However, despite several large-scale studies, our current knowledge about protein complexes is still quite limited, thus advocating the use of in silico predictions to ...
Roland A. Pache, Patrick Aloy
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Journal of Clinical and Translational Science, 2022 For decades, the research community called for streamlined Institutional Review Board (IRB) review processes for multisite studies. Department of Health and Human Services and National Institutes of Health (NIH) recognized this need and implemented ...
Emily Sheffer Serdoz +7 more
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Genome Medicine, 2021 Background In spite of many years of research, our understanding of the molecular bases of Alzheimer’s disease (AD) is still incomplete, and the medical treatments available mainly target the disease symptoms and are hardly effective.
Eduardo Pauls +13 more
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Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38α
Nature Communications, 2023 Many functional aspects of the protein kinase p38α have been illustrated by more than three hundred structures determined in the presence of reducing agents.
Joan Pous +11 more
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Ethics in academic research and scholarship: An elucidation of the principles and applications
Journal of Global Education and Research, 2019 Responsible, respectable, and successful engagement in research and scholarship in academia requires adherence to certain basic professional ethical principles to sustain the fidelity of academic work and the integrity of the researcher-scholar.
Olajide Agunloye
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Blockchain in Healthcare Today, 2018 Clinical research and health information data sharing are but ripples in a growing wave of reimagined applications of distributed ledger technologies beyond the digital marketplace for which they were originally created.
Vaso Rahimzadeh
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