Results 71 to 80 of about 173,627 (382)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Multi-institutional generalizability of a plan complexity machine learning model for predicting pre-treatment quality assurance results in radiotherapy

Physics and Imaging in Radiation Oncology
Background and purpose: Treatment plans in radiotherapy are subject to measurement-based pre-treatment verifications. In this study, plan complexity metrics (PCMs) were calculated per beam and used as input features to develop a predictive model. The aim
Michaël Claessens, Geert De Kerf, Verdi Vanreusel, Isabelle Mollaert, Victor Hernandez, Jordi Saez, Núria Jornet, Dirk Verellen   +7 more
doaj   +1 more source

Exceptionally active iridium evolved from a pseudo-cubic perovskite for oxygen evolution in acid

Nature Communications, 2019
Exploring robust catalysts for water oxidation in acidic electrolyte is challenging due to the limited material choice. Iridium (Ir) is the only active element with a high resistance to the acid corrosion during water electrolysis.
Yubo Chen, Haiyan Li, Jingxian Wang, Yonghua Du, S. Xi, Yuanmiao Sun, M. Sherburne, J. Ager, A. Fisher, Zhichuan J. Xu   +9 more
semanticscholar   +1 more source

Recent advances in understanding oxygen evolution reaction mechanisms over iridium oxide

Inorganic Chemistry Frontiers, 2021
Recent spectroscopic and computational studies concerning the oxygen evolution reaction over iridium oxides are reviewed to provide the state-of-the-art understanding of its reaction mechanism.
Takahiro Naito, Tatsuya Shinagawa, Takeshi Nishimoto, K. Takanabe   +3 more
semanticscholar   +1 more source

Influence of structural distortions on the Ir magnetism in Ba2-xSrxYIrO6 double perovskites

, 2016
We explore the relative strengths of spin orbit coupling and crystal field splitting in the Ir5+ compounds Ba2-xSrxYIrO6. In the case of strong spin orbit coupling and regular Ir5+ octahedra, one expects a nonmagnetic J = 0 state; in the case of ...
Badoe Jr., Daniel, Cava, R. J., Phelan, Brendan F., Seibel, Elizabeth M., Xie, Weiwei   +4 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Balancing activity, stability and conductivity of nanoporous core-shell iridium/iridium oxide oxygen evolution catalysts

Nature Communications, 2017
Production of affordable, clean hydrogen relies on efficient oxygen evolution, but improving catalytic performance for the reaction in acidic media is challenging.
Yong-Tae Kim, Pietro Papa Lopes, Shin-Ae Park, A-Yeong Lee, Jinkyu Lim, Hyunjoo Lee, Seoin Back, Yousung Jung, Nemanja Danilovic, Vojislav Stamenkovic, Jonah Erlebacher, Joshua Snyder, Nenad M. Markovic   +12 more
doaj   +1 more source

Electronic Structure of Hyperkagome Na4Ir3O8

, 2010
We investigate the electronic structure of the frustrated magnet Na4Ir3O8 using density functional theory. Due to strong spin-orbit coupling, the hyperkagome lattice is characterized by a half-filled complex of states, making it a cubic iridium analogue ...
M. R. Norman, T. Micklitz, W. H. Press
core   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Fine structure of the atomic scattering factors near the iridium L-edges [PDF]

, 2022
Hisamitsu Awaki, Yoshitomo Maeda, Hironori Matsumoto, Marcos Bavdaz, Finn E. Christensen, Maximilien J. Collon, Desirée Della Monica Ferreira, Kazunori Ishibashi, Sonny Massahi, Takuya Miyazawa, Sara Svendsen, Keisuke Tamura   +11 more
openalex   +1 more source