Results 151 to 160 of about 3,601 (174)

Irinotecan Hydrochloride Injection

2022
openaire   +1 more source

Individual differences in rate-limiting reactions during metabolism of irinotecan hydrochloride.

Gan to kagaku ryoho. Cancer & chemotherapy, 2009
Irinotecan hydrochloride (CPT-11) is converted to SN-38 by carboxylesterase, SN-38 is conjugated by UDP-glucuronosyl- transferase (UGT) to SN-38G. Individual differences in enzyme activity influence the efficacy of this anticancer agent and the adverse reactions it induces.
Shigefumi, Morimoto, Ichiro, Matsuura, Yoshiharu, Shono, Tetsuya, Horiuchi, Yumi, Nakajima, Takashi, Miyabe, Yoshimi, Hachino, Kenji, Hasegawa, Kazuyo, Matsuyama, Yoshikazu, Fujita, Katsuyoshi, Tabuse   +10 more
openaire   +1 more source

A validated UPLC-MS/MS method to determine free and total irinotecan and its two metabolites in human plasma after intravenous administration of irinotecan hydrochloride liposome injection

Journal of Pharmaceutical and Biomedical Analysis, 2019
Quankun Zhuang, Ji Jiang
exaly  

Irinotecan hydrochloride trihydrate loaded folic acid-tailored solid lipid nanoparticles for targeting colorectal cancer: development, characterization, andin vitrocytotoxicity study using HT-29 cells

Journal of Microencapsulation, 2019

exaly  

Relevance of Irinotecan Hydrochloride-Induced Diarrhea to the Level of Prostaglandin E2 and Water Absorption of Large Intestine in Rats

The Japanese Journal of Pharmacology, 1997
Yoshio Kase, Tetsuya Kamataki
exaly  

Preventive Effects of Hange-shashin-to on Irinotecan Hydrochloride-Caused Diarrhea and Its Relevance to the Colonic Prostaglandin E2 and Water Absorption in the Rat

The Japanese Journal of Pharmacology, 1997
Yoshio Kase, Masaki Aburada, Tetsuya Kamataki   +2 more
exaly  

Clinical effects of irinotecan hydrochloride in combination with cisplatin as neoadjuvant chemotherapy in locally advanced cervical cancer

Gynecologic Oncology, 2011
Liu Ji-Hong, Ji-Hong Liu
exaly  

Combination Phase I/II Study of Irinotecan Hydrochloride (CPT-11) and Carboplatin in Relapsed or Refractory Non-Hodgkin's Lymphoma

Japanese Journal of Clinical Oncology, 1996
K Tobinai, R Ohno, Y Ariyoshi
exaly  

Effect of genistein, a natural soy isoflavone, on the pharmacokinetics and intestinal toxicity of irinotecan hydrochloride in rats

Journal of Pharmacy and Pharmacology, 2012
Tomoharu Yokooji, Nobuhiro Mori, Teruo Murakami   +2 more
exaly  

Complete response to irinotecan hydrochloride and nedaplatin in a patient with advanced ovarian clear cell carcinoma

International Journal of Clinical Oncology, 2004
Masato Nishida, Hajime Tsunoda, Nishida Masato   +2 more
exaly