Results 101 to 110 of about 19,243 (300)

Egzersiz, İrisin ve Obezite

Gaziantep Üniversitesi Spor Bilimleri Dergisi, 2022
Gelişmiş ve gelişmekte olan ülkelerdeki şehir hayatının hareketsiz yaşamı, besinsel ürünlere kolay ulaşabilmeyi ve fas food kültürünü yaygınlaştırdığı görülmektedir. Yeni yaşam tarzı hem halk sağlığını tehdit etmekte hem de sistemik metabolik fonksiyon bozukluklarına kılavuzluk ederek obezite gibi hastalıkların yaygınlaşmasına neden olmaktadır.
Salih ÖNER, Yavuz YASUL
openaire   +3 more sources

Senkyunolide I Improves Septicemia‐Induced Brain Dysfunction via Regulating Nrf2 and Astrocyte Activity.

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Senkyunolide I (Sen I) has a protective effect on the blood–brain barrier (BBB) in rats with sepsis‐associated encephalopathy (SAE). This study investigated whether Sen I regulates Nrf2 to ameliorate sepsis‐induced brain dysfunction (SIBD). Sixty rats were randomly assigned into Sham group, SAE group (Model group), SAE + Sen I group (72 mg/kg,
Haohao Cao, Tao Liu, Meixia Xu
wiley   +1 more source

3-Center Studie zur Untersuchung von Auswirkungen der Ganzkörpervibrationstherapie bei Patienten mit Lungenfibrose: eine randomisiert kontrollierte Studie. Effekte auf serumspezifische Biomarker, Inflammationsparameter, gesundheitsbezogene Lebensqualität und den 6-Minutengehtest als Nebenergebnis. [PDF]

, 2020
Hintergrund: Zahlreiche wissenschaftliche Studien deuten auf positive trainingstherapeutische Effekte bei Patienten mit interstitiellen Lungenerkrankungen (ILD ) hin.
Kölpin, Janina
core   +1 more source

Irisin ameliorates diabetic kidney disease by restoring autophagy in podocytes

The FASEB Journal, 2023
Many studies have highlighted the importance of moderate exercise. While it can attenuate diabetic kidney disease, its mechanism has remained unclear. The level of myokine irisin in plasma increases during exercise.
W. Lai, Dan Luo, Yin Li, Yuanqing Li, Qianqian Wang, Zhaoyong Hu, Z. Ye, Hui Peng   +7 more
semanticscholar   +1 more source

Mitochondrial dynamics in autoimmune diseases

Rheumatology &Autoimmunity, EarlyView.
Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma, Cheng Zhang, Jiaqing Liu, Jinyi Ren, Xia Li, Ying Zhao   +5 more
wiley   +1 more source

Exercise-induced modulation of myokine irisin on muscle-bone unit in the rat model of post-traumatic osteoarthritis

Journal of Orthopaedic Surgery and Research
Background and aim Post-traumatic osteoarthritis (PTOA) is a subtype of osteoarthritis (OA). Exercise may produce and release the myokine irisin through muscle fiber contraction.
Xingru Shang, Xiaoxia Hao, Wenjie Hou, Jiawei Liu, Ruimin Chi, Xiaofeng Deng, Chunran Pan, Tao Xu   +7 more
semanticscholar   +1 more source

Once-Daily Subcutaneous Irisin Administration Mitigates Depression- and Anxiety-like Behavior in Young Mice

International Journal of Molecular Sciences, 2023
Major depression is one of the most common psychiatric disorders worldwide, usually associated with anxiety. The multi-etiological nature of depression has increased the search for new antidepressant molecules, including irisin, for which, in a previous ...
P. Pignataro, M. Dicarlo, Clelia Suriano, L. Sanesi, Roberta Zerlotin, G. Storlino, A. Oranger, C. Zecca, M. T. Dell’Abate, G. Mori, M. Grano, S. Colucci, G. Colaianni   +12 more
semanticscholar   +1 more source

Formation of a β‐Endorphin Corona Mitigates Alzheimer's Amyloidogenesis

Small, EarlyView.
This study revealed the molecular mechanism of exercise‐induced β‐endorphin in suppressing the toxicity of Alzheimer's Aβ in vitro, in vivo and in silico. Abstract Senile plaques, comprised of nanosized aggregates of amyloid‐β (Aβ) peptides in the brain, are a pathological hallmark of Alzheimer's disease (AD).
Yunxiang Sun, Nicholas Andrikopoulos, Guofang Zhang, Yuying Liu, Xiufang Liang, Dongjie Li, Xiaoman Suo, Yue Wang, Yuhuan Li, Chuang Wang, Yang Li, Pu Chun Ke, Feng Ding   +12 more
wiley   +1 more source

Alterations of the Adipo–Myokine Irisin in Sepsis and Septic Shock: Diagnostic and Prognostic Implications

Biomolecules
Irisin, a novel adipo-myokine with metabolic regulatory functions, exerts anti-inflammatory, antioxidant, and anti-apoptotic actions that may confer protection against sepsis-induced organ injury in experimental studies.
I. Karampela, N. Vallianou, Dimitrios Tsilingiris, G. Christodoulatos, Sotiria Psallida, D. Kounatidis, T. Stratigou, I. Marinou, E. Vogiatzakis, M. Dalamaga   +9 more
semanticscholar   +1 more source

Anti-inflammatory effect of Irisin on LPS-stimulated macrophages through inhibition of MAPK pathway.

Physiological Research, 2023
This study aimed to investigate the effect of irisin on LPS-induced inflammation in RAW 264.7 macrophages through inhibition of the mitogen-activated protein kinase (MAPK) pathway.
Y. Ma, Y. Du, J. Yang, Q. He, H. Wang, X. Lin   +5 more
semanticscholar   +1 more source