Results 41 to 50 of about 102,997 (247)

Iron intake, body iron status, and risk of breast cancer: a systematic review and meta-analysis

BMC Cancer, 2019
Background Iron has been shown to promote breast carcinogenesis in animal models through generation of oxidative stress and interaction with estrogen. Heme iron, which is found exclusively in animal-sourced foods, is suggested to have a more detrimental ...
Vicky C. Chang, Michelle Cotterchio, Edwin Khoo   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Pengaruh Asupan Protein dan Zat Besi (Fe) terhadap Kadar Hemoglobin pada Wanita Bekerja

Jurnal Kesehatan, 2017
Anemia is a condition where the hemoglobin (Hb) is lower than the normal value according to age and sex of a person caused by certain factors, including intake of nutrients one protein and iron, with the percentage of women in Indonesia who have anemia ...
Agus Hendra Al Rahmad
doaj   +1 more source

Perbedaan Asupan Zat Besi Ibu Hamil Anemia dan non-Anemia di Jakarta Timur

Indonesian Journal of Human Nutrition, 2022
Dalam kehamilan anemia merupakan faktor penting yang terkait dengan peningkatan risiko kematian ibu anak. Asupan zat besi dan bioavailabilitas zat besi penting untuk pencegahan anemia defisiensi besi. Penelitian ini bertujuan untuk menganalisis perbedaan
Isti Istianah, Sri Fauziana, Adhila Fayasari   +2 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Dietary haem-iron and iron supplementation in the third trimester are associated with gestational diabetes mellitus risk: cross-sectional analysis of a prospective study

Heliyon
Gestational diabetes mellitus (GDM) poses significant short- and long-term risks to both mother and foetus. Understanding how maternal iron intake from foods and supplements influences GDM risk is crucial.
Heng Yaw Yong, Zalilah Mohd Shariff, Su Peng Loh, Barakatun Nisak Mohd Yusof, Nor Baizura Md Yusop   +4 more
doaj   +1 more source

Iron intake is positively associated with viral load in antiretroviral naïve Brazilian men living with HIV [PDF]

Memorias do Instituto Oswaldo Cruz, 2020
BACKGROUND Iron homeostasis contribute for the human immunodeficiency virus (HIV) pathogenesis. OBJECTIVES We assessed the iron intake pattern in antiretroviral naïve Brazilian men living with HIV correlating with clinical and nutritional parameters.
Juliana Lauar Gonçalves, Maria Clara Amorim Silva, Eric Henrique Roma, Beatriz Grinsztejn, Alberto dos Santos de Lemos, Nathalia Gorni, Adele Moura Cruz, Cristiane Fonseca de Almeida, Marcel de Souza Borges Quintana, Maria da Gloria Bonecini-Almeida, Patrícia Dias de Brito   +10 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Dietary iron intake, body iron stores, and the risk of type 2 diabetes: a systematic review and meta-analysis

BMC Medicine, 2012
Background Excess iron has been shown to induce diabetes in animal models. However, the results from human epidemiologic studies linking body iron stores and iron intake to the risk of type 2 diabetes mellitus (T2DM) are conflicting.
Bao Wei, Rong Ying, Rong Shuang, Liu Liegang   +3 more
doaj   +1 more source