Results 41 to 50 of about 291,425 (266)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Sensorless Control of High-Speed Motors Subject to Iron Loss

open access: yesEnergies, 2022
It is widely recognized that the iron loss produced by motors at high speeds will directly affect the angle and size of the back electromotive force, and, therefore, it cannot be ignored.
Yang Cao, Jian Guo
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Losses in Efficiency Maps of Electric Vehicles: An Overview

open access: yesEnergies, 2021
In some applications such as electric vehicles, electric motors should operate in a wide torque and speed ranges. An efficiency map is the contour plot of the maximum efficiency of an electric machine in torque-speed plane.
Emad Roshandel   +4 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Calculation and Study of Permanent Magnet Synchronous Motor Iron Loss

open access: yesKongzhi Yu Xinxi Jishu, 2015
Taking into account of rotational magnetization and harmonic magnetic field, a calculation method of iron loss for permanent magnet synchronous motor (PMSM) was presented , which was based on finite element analysis and Bertotti iron loss calculation ...
PENG Jun, LI Yifeng, FU Minli
doaj  

Effects of Magnetic Powder Filling Ratio on the Characteristics of a Magnetic Composite Core Motor

open access: yesIEEE Access
Magnetic-composite materials, comprising soft magnetic powder and a resin binder, are characterized by excellent machinability and low iron loss. Motors with stator cores made of magnetic-composite materials (magnetic composite core (MCC) motors) can ...
Takashi Nakamura   +4 more
doaj   +1 more source

A Combined Experimental and Finite Element Analysis Method for the Estimation of Eddy-Current Loss in NdFeB Magnets

open access: yesSensors, 2014
NdFeB permanent magnets (PMs) are widely used in high performance electrical machines, but their relatively high conductivity subjects them to eddy current losses that can lead to magnetization loss.
Radu Fratila   +3 more
doaj   +1 more source

Empirical Implementation of the Steinmetz Equation to Compute Eddy Current Loss in Soft Magnetic Composite Components

open access: yesIEEE Access, 2022
Finite element analysis of magnetic materials allows accurate prediction of losses and is crucial in the design of electromagnetic devices and products.
Mehmet C. Kulan   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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