Results 61 to 70 of about 1,167,831 (311)

Inhibition of Xanthomonas fragariae, Causative Agent of Angular Leaf Spot of Strawberry, through Iron Deprivation. [PDF]

open access: yes, 2016
In commercial production settings, few options exist to prevent or treat angular leaf spot (ALS) of strawberry, a disease of economic importance and caused by the bacterial pathogen Xanthomonas fragariae.
Gebben, Samantha J   +4 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A New Application of Transient Recorder to Magnetic Measurements (Part I: Core Loss Measurement at Very Low Frequencies) [PDF]

open access: yes, 1976
A new method have been developed based upon analogue-to-digital conversion techniques and memories. The method involves the scaling of operating frequency from "real" to "optimum" for the power loss measurement.
Ishihara, Yoshiyuki   +3 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Altered sterol metabolism in budding yeast affects mitochondrial iron–sulfur (Fe-S) cluster synthesis [PDF]

open access: yes, 2018
Ergosterol synthesis is essential for cellular growth and viability of the budding yeast Saccharomyces cerevisiae, and intracellular sterol distribution and homeostasis are therefore highly regulated in this species. Erg25 is an iron-containing C4-methyl
Bard, Martin   +7 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Moisture movement in bulk stockpiles [PDF]

open access: yes, 1995
Both drainage and evaporation are possible mechanisms for moisture loss in iron-ore and coal stockpiles. Some simple models are used to study both these mechanisms for various stages of stockpiling.
Fulford, G., McElwain, S.
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The Leaching of Iron and Loss of Phosphate in Acid Sulphate Soil Due to Rice Straw and Phosphate Fertilizer Application [PDF]

open access: yes, 2012
Low phosphorus (P) availability and high iron (Fe) concentration are the dominant characteristics of acid sulphate soils (ASS).  Optimum agricultural management practices are required to leach the excess Fe2+  and to prevent or minimize loss
Fahmi, A. (Arifin)   +2 more
core  

Searching for the missing iron in the core of the Centaurus cluster

open access: yes, 2013
We re-analyse a combined 198 ks Chandra observation of NGC4696, the brightest galaxy of the Centaurus cluster. We extract temperature and metallicity profiles from the data, and we confirm the presence of a sharp drop in iron abundance, from ~1.8 Zsolar ...
Fabian, A. C.   +2 more
core   +1 more source

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