Results 71 to 80 of about 2,003,726 (300)

Iron and Iron Metabolism

Güncel Pediatri, 2012
Iron is an essential element for almost all living organisms except some bacteria. A great number of new articles related to the iron metabolism have been published in recent years explaining new findings. Hepsidine, a peptide hormon, that is recently found, regulates iron methabolism by effecting iron absorbsion from gut, secreting iron from hepatic ...
Melike Sezgin Evim, Birol Baytan, Adalet Meral Güneş   +2 more
openaire   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Safety Aspects of Iron in Food [PDF]

, 2001
During the last decades efforts regarding dietary iron supply focused mostly on the prevention of deficiencies, especially during growth and pregnancy.
Schümann, Klaus
core   +1 more source

S282: ERYTHROPOIESIS INDUCTION THROUGH BONE MARROW TFR2 DELETION REDUCES BLOOD GLUCOSE LEVELS IN WILD-TYPE AND Β-THALASSEMIC MICE

HemaSphere, 2023
Simona Maria DI Modica, Celia Cordero-Sanchez, Mariateresa Pettinato, Alessia Pagani, Laura Silvestri, Antonella Nai   +5 more
doaj   +1 more source

Iron as an immunometabolic signal in infection and inflammation

Frontiers in Immunology
Iron availability is dynamically remodeled during infection and inflammation and has traditionally been interpreted within the framework of nutritional immunity, where iron sequestration restricts microbial growth. Increasing evidence, however, indicates
Alexander Hoffmann, Alexander Hoffmann, Laura Homs Pérez, Laura Homs Pérez, Günter Weiss, Günter Weiss   +5 more
doaj   +1 more source

Iron and leukemia: new insights for future treatments

Journal of Experimental & Clinical Cancer Research, 2019
Iron, an indispensable element for life, is involved in all kinds of important physiological activities. Iron promotes cell growth and proliferation, but it also causes oxidative stress damage.
Fang Wang, Huanhuan Lv, Bin Zhao, Liangfu Zhou, Shenghang Wang, Jie Luo, Junyu Liu, Peng Shang   +7 more
doaj   +1 more source

Identification of Iron Metabolism

IFAC Proceedings Volumes, 1982
Abstract A methodology for the study of erythroid disorders by means of a mathematical model of iron kinetics and classification techniques are presented. Iron flows along the pathway linking iron pools in the body can be quantitated by estimating model parameters from tracer data. This provides a quantitative assessment of erythropoiesis, since iron
Berzuini, Carlo; id_orcid 0000-0001-6056-0489, Quaglini, Silvana, Stefanelli, Mario   +2 more
openaire   +2 more sources

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source

A study of zinc transporter 1 and its role in Type 3 Haemochromatosis [PDF]

, 2009
Hereditary haemochromatosis is an autosomal recessive disorder of iron metabolism, characterised by increased iron absorption and progressive iron accumulation particularly in the liver.
Parkinson, Liza
core  

Iron metabolism of in­testinal mucosa in various blood diseases [PDF]

, 1964
For the investigation of iron metabolism in the intestinal mucosa in various　blood diseases, intestinal biopsy (duodenum) was performed on 10 healthy controls　and 35 cases with various blood diseases.
Kimura, Ikuro, Tsuchida, Junichiro, Kodani, Hidenari   +2 more
core   +1 more source