Results 91 to 100 of about 2,003,726 (300)

The effect of iron on hepatitis C virus replication [PDF]

, 2011
Hepatitis C virus (HCV) is a small RNA encoded virus that causes acute and chronic infections of the liver and is associated with fibrosis, cirrhosis, hepatocellular carcinoma and end-stage liver disease.
Clark, Hayley
core  

Benefits and risks of iron supplementation in anemic neonatal pigs. [PDF]

, 2010
Iron deficiency is a common health problem. The most severe consequence of this disorder is iron deficiency anemia (IDA), which is considered the most common nutritional deficiency worldwide. Newborn piglets are an ideal model to explore the multifaceted
Thibaudeau, Olivier, Oliński, Ryszard, Zabielski, Romuald, Usińska, Agnieszka, Smuda, Ewa, Kowalczyk, Paweł, Canonne-Hergaux, François, Woliński, Jarosław, Dziaman, Tomasz, Starzyński, Rafał R, Tudek, Barbara, Gralak, Mikołaj A, Lipiński, Paweł   +12 more
core   +2 more sources

Prevalence of Dietary Supplement Use and Potential Medication Interactions Among Adults With Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize the prevalence and correlates of dietary supplement use, identify commonly used supplements, and evaluate potential supplement–medication interactions among adults with systemic lupus erythematosus (SLE).
Sarah L. Patterson, Russell Ellyson, Jessica Fitzpatrick, Ghizlane Yaakoubi, Bradley Pearce, S. Sam Lim, Jinoos Yazdany, Laura C. Plantinga   +7 more
wiley   +1 more source

S285: DISSECTING THE ROLE OF THE IMMUNOPHILIN FKBP12 IN HEPCIDIN REGULATION

HemaSphere, 2023
Mariateresa Pettinato, Alessandro Dulja, Silvia Colucci, Valeria Furiosi, Franca Fette, Andrea Steinbicker, Martina Muckenthaler, Antonella Nai, Alessia Pagani, Laura Silvestri   +9 more
doaj   +1 more source

Iron, hepcidin and the metal connection.

Frontiers in Pharmacology, 2014
Identification of new players in iron metabolism, such as hepcidin, which regulates ferroportin and divalent metal transporter 1 expression, has improved our knowledge of iron metabolism and iron-related diseases. However, from both experimental data and
Olivier eLoréal, Olivier eLoréal, Olivier eLoréal, Thibault eCavey, Thibault eCavey, Thibault eCavey, Edouard eBardou-Jacquet, Edouard eBardou-Jacquet, Edouard eBardou-Jacquet, Pascal eGuggenbuhl, Pascal eGuggenbuhl, Pascal eGuggenbuhl, Martine eRopert, Martine eRopert, Martine eRopert, Pierre eBrissot, Pierre eBrissot, Pierre eBrissot   +17 more
doaj   +1 more source

Non‐Additive Criteria Assessment in Sustainability Evaluation of High Entropy Alloys: A Toxicity‐Weighted Framework

Advanced Engineering Materials, EarlyView.
Sustainability assessment requires methodologies that appropriately distinguish between additive and non‐additive material properties. A toxicity‐weighted scoring system is developed and applied that accounts for the disproportionate influence of highly toxic constituents through nonlinear weighting functions, providing more realistic estimates than ...
Seth Mehalic, Oladele A. Ogunseitan, Julie M. Schoenung   +2 more
wiley   +1 more source

Melanin's Role in Balancing Mechanical Strength and Reproductive Output in Environmentally Stressed Fungal Spores

Advanced Functional Materials, EarlyView.
Melanin content directly controls fungal spore mechanical properties, with pigmented spores achieving rupture forces two orders of magnitude higher than hyaline spores. Environmental stress drives this quantity‐quality tradeoff; stressed species invest energy in melanin‐reinforced, mechanically superior thick‐walled, super‐hydrophobic spores, while ...
Atul Agrawal, Steven E. Naleway
wiley   +1 more source

Crossroads of Iron Metabolism and Inflammation in Colorectal Carcinogenesis: Molecular Mechanisms and Therapeutic Perspectives [PDF]

Background/Objectives: Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide. Iron metabolism and chronic inflammation are two interrelated processes that significantly influence the initiation and progression of CRC.
Nahid Ahmadi, Vinod Gopalan, Gihani Vidanapathirana, Ahmadi, N, Vidanapathirana, G, Gopalan, V   +5 more
core   +1 more source

Macrophage-specific LAMTOR2 deletion disrupts systemic iron homeostasis in mice

Haematologica
At the center of iron homeostasis, macrophages play a crucial role by phagocytosing senescent erythrocytes while nursing erythrocyte progenitors. A major route of cellular iron acquisition occurs via transferrin receptor 1 (TFR1)-mediated endocytosis of
Laura Homs Pérez, Iana Portnaia, Markus Seifert, Sylvia Berger, Stephanie Waich, Lukas Müller, Nidhi Srinivasan, Lukas A. Huber, Martin Offterdinger, Richard Hilbe, Alexander Hoffmann, Manuel Grander, David Haschka, Günter Weiss   +13 more
doaj   +1 more source

An Integrated Oxygen‐Supplying Device and Predictive Multiphysics Model for Extended Ambient Transport of Insulin‐Producing Cells

Advanced Functional Materials, EarlyView.
Cell therapies typically rely on cold‐chain logistics and cryopreservation, limiting access and compromising cell quality. Here, a dual‐chamber device separates an oxygen‐supplying chamber from a hyaluronic acid cargo chamber, sustaining oxygen delivery for over 70 h and enabling ambient‐temperature shipment.
Daniel A. Domingo‐Lopez, Ruth Tarpey, Benjamin Brennan, Bryan D. Boyle, Amir M. Alsharabasy, Abhik Mallick, Gabriella Bellavia, Abhay Pandit, Garry P. Duffy, Ruth E. Levey   +9 more
wiley   +1 more source