Results 111 to 120 of about 254,938 (314)

Elucidating Iron Metabolism through Molecular Imaging

Current Issues in Molecular Biology
Iron is essential for many physiological processes, and the dysregulation of its metabolism is implicated in the pathogenesis of various diseases.
Feifei Liao, Wenwen Yang, Linzi Long, Ruotong Yu, Hua Qu, Yuxuan Peng, Jieming Lu, Chenghuan Ren, Yueqi Wang, Changgeng Fu   +9 more
doaj   +1 more source

Influence of different iron availability on phosphoenolpiruvate carboxilase and malate dehydrogenase in roots of maize (Zea Mays L.) plants grown under iron deficiency

, 2010
The effect of the different nitrate availability on some enzymatic activities has been evaluated in iron deficient and iron sufficient maize plants (Zea mays L.).
Adalgisa Belligno, Marco Antonio Russo
core   +1 more source

Ascorbate and Tumor Cell Iron Metabolism: The Evolving Story and Its Link to Pathology

, 2020
Significance: Vitamin C or ascorbate (Asc) is a water-soluble vitamin and an antioxidant that is involved in many crucial biological functions. Asc's ability to reduce metals makes it an essential enzyme cofactor.
Lane, Darius JR, Gholam Azad, Mahan, Bae, Dong-Hun, Richardson, Des R, Jansson, Patric J, Kalinowski, Danuta S   +5 more
core   +1 more source

Climate Change Threatens Micronutrient Density of European Winter Wheat

Advanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao, Jennifer Michel, Eline Lorer, Markus Weinmann, Jacques Le Gouis, Claire Léon, Sibille Perrochon, David Alvarez, Vincent Leemans, Iñaki Balanzategui Guijarro, Jordi Moya Laraño, Sara Sánchez Moreno, Symanczik Sarah, Waibel Matthias, Hervé Vanderschuren, Cécile Thonar, Pierre Delaplace, Dominique Van Der Straeten   +17 more
wiley   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

Clinical Characteristics, Iron Metabolism and Neuroinflammation: New Insight into Excessive Daytime Sleepiness in Parkinson’s Disease

, 2021
Yang Hu,1 Peng Guo,1 Teng-Hong Lian,1 Li-Jun Zuo,1 Shu-Yang Yu,1 Li Liu,2 Zhao Jin,1 Qiu-Jin Yu,1 Rui-Dan Wang,1 Li-Xia Li,2 Ying-Shan Piao,3 Wei Zhang3– 7 1Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing ...
Li LX, Zhang W, Yu SY, Hu Y, Liu L, Lian TH, Yu QJ, Piao YS, Zuo LJ, Jin Z, Guo P, Wang RD   +11 more
core  

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

Advanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo, Qingran Guan, Guanyu Qiao, Lixue Zhang, Man Liu, Zhen Li, Qingbiao Yang, Meili Shen, Linlin Liu, Yapeng Li   +9 more
wiley   +1 more source

P1496: TRANSFERRIN NON-CODING VARIANTS CAUSE MRNA DESTABILISATION IN CONGENITAL HYPOTRANSFERRINEMIA

HemaSphere, 2023
Xenia Ferrer, Lídia Romero-Cortadellas, Cristina Diaz-de-Heredia, Katja Moser, Ilona Kleine Budde, Mayka Sanchez   +5 more
doaj   +1 more source

Acute kidney injury and iron metabolism: A narrative review focusing on pathophysiology and therapy

Smart Molecules
Acute kidney injury (AKI) represents a substantial challenge to public health and is characterized by elevated occurrence and fatality rates. In the last 3 decades, the disruption of iron homeostasis and the cytotoxic effects mediated by iron have been ...
Xinyu Tan, Man Li, Jing Chen, Gang Liu, Zhixiang Lu   +4 more
doaj   +1 more source

Integrating multi-omics techniques and in vitro experiments reveals that GLRX3 regulates the immune microenvironment and promotes hepatocellular carcinoma cell proliferation and invasion through iron metabolism pathways

Frontiers in Immunology
BackgroundHepatocellular carcinoma (HCC) is a common malignancy worldwide, and its development is closely related to abnormalities in iron metabolism. This study aims to systematically analyze changes in iron metabolism in the tumor microenvironment of ...
Yang Li, Yuan Chen, Yuan Chen, Yang Zhang, Yunsheng Fang, Yunsheng Fang, Ling Wu, Ying Zhao, Danqiong Wang, Xiaoyuan Qiao   +9 more
doaj   +1 more source