Results 1 to 10 of about 30,077 (251)

Hepcidin Therapeutics [PDF]

Pharmaceuticals, 2018
Hepcidin is a key hormonal regulator of systemic iron homeostasis and its expression is induced by iron or inflammatory stimuli. Genetic defects in iron signaling to hepcidin lead to “hepcidinopathies„ ranging from hereditary hemochromatosis ...
Kostas Pantopoulos, Angeliki Katsarou
exaly   +6 more sources

IL-1 beta-mediated macrophage-hepatocyte crosstalk upregulates hepcidin under physiological low oxygen levels

Redox Biology, 2019
In mammals, the iron masterswitch hepcidin efficiently controls iron recycling by the macrophage-liver axis but the exact interplay between macrophages and hepatocytes remains poorly understood.
Sebastian Mueller, Vanessa Rausch
exaly   +3 more sources

Potential Usefulness of Urinary Hepcidin Measurement for Iron Deficiency Anemia in Female Athletes [PDF]

European Journal of Sport Science
Hepcidin is a key regulator of iron metabolism and has been proposed as a biomarker for detecting iron deficiency. This study examined serum hepcidin and non‐invasively measured urinary hepcidin in 260 female athletes to assess their potential utility in
Haruo Hanawa, Hiromi Inaba, Fumi Hoshino, Mutsuaki Edama, Chie Sekine, Takanori Kikumoto, Tomonobu Ishigaki, Yuiko Matsuura, Go Omori   +8 more
doaj   +2 more sources

Serum hepcidin and erythropoietin in relation to anemia in non-diabetic chronic kidney disease: a cross-sectional study. [PDF]

Sci Rep
Gamal M, Abdel-Rahman AM, Elwahab AA, Refaie H, El-Halawani SM, Mortada WL, Sobh M.   +6 more
europepmc   +3 more sources

Nanoparticle-encapsulated hepcidin as a dietary strategy to improve growth, biochemical status, and immune responses in common carp (<i>Cyprinus carpio</i>) pre- and post-<i>Aeromonas hydrophila</i> challenge. [PDF]

Vet Anim Sci
Ahmadifar E, Mohammadzadeh S, Moghadam MS, Khajeh M, Adineh H, Yilmaz S, Sheikhzadeh N, Khanzadeh M.   +7 more
europepmc   +3 more sources

Activating Cannabinoid receptor 2 alleviates iron overload-induced liver damage via dual modulation of STAT3/hepcidin and Nrf2/FPN1 pathways. [PDF]

Mol Biomed
Deng H, Ren Y, Sui Y, Ma Z.
europepmc   +3 more sources

Hepcidin and Cardiovascular Events in CKD With and Without Dialysis. [PDF]

Kidney Int Rep
Fujimoto Y, Matsue Y, Nakade T, Singh YS, Akama Y, Nakamura Y, Cao J, Aikawa T, Sakamaki K, Minamino T.   +9 more
europepmc   +3 more sources

Physiologically based serum hepcidin and ferritin thresholds identify similar onsets of iron-deficient erythropoiesis in adult blood donors. [PDF]

Br J Haematol
Addo OY, Brittenham GM, Mei Z, Jefferds MED, Flores-Ayala RC, Fliginger D, Lipschitz J, Qiu A, Spitalnik SL, Hod EA.   +9 more
europepmc   +3 more sources

Sappanwood extract modulates hepatic structure-function in hepatomegaly and hepcidin related iron regulatory pathways in a phenylhydrazine induced hemolytic anemia rat model relevant to thalassemia. [PDF]

Animal Model Exp Med
Pratama MI, Safitri R, Malini DM, Syamsunarno MRAA, Ghozali M, Madihah M.   +5 more
europepmc   +3 more sources

Low Serum Hepcidin in Patients with Autoimmune Liver Diseases. [PDF]

PLoS ONE, 2015
Hepcidin, a liver hormone, is important for both innate immunity and iron metabolism regulation. As dysfunction of the hepcidin pathway may contribute to liver pathology, we analysed liver hepcidin mRNA and serum hepcidin in patients with chronic liver ...
Aggeliki Lyberopoulou, Georgia Chachami, Nikolaos K Gatselis, Eleni Kyratzopoulou, Asterios Saitis, Stella Gabeta, Petros Eliades, Efrosini Paraskeva, Kalliopi Zachou, George K Koukoulis, Avgi Mamalaki, George N Dalekos, George Simos   +12 more
doaj   +1 more source