Results 41 to 50 of about 30,077 (251)

Increased serum hepcidin-25 level and increased tumor expression of hepcidin mRNA are associated with metastasis of renal cell carcinoma

open access: yesBMC Cancer, 2009
Background Hepcidin has an important role in iron metabolism. We investigated whether hepcidin was involved in renal cell carcinoma (RCC). Methods We measured serum hepcidin-25 levels in 32 patients by liquid chromatograpy (LC)-mass spectrometry (MS)/MS,
Abe Hideyuki   +4 more
doaj   +1 more source

Hepcidin expression in iron overload diseases is variably modulated by circulating factors. [PDF]

open access: yesPLoS ONE, 2012
Hepcidin is a regulatory hormone that plays a major role in controlling body iron homeostasis. Circulating factors (holotransferrin, cytokines, erythroid regulators) might variably contribute to hepcidin modulation in different pathological conditions ...
Giulia Ravasi   +11 more
doaj   +1 more source

Hepcidin correlates with interleukin-1β and interleukin-6 but not iron deficiency in children with Helicobacter pylori infection

open access: yesPediatrics and Neonatology, 2018
Background: Helicobacter pylori infection is associated with iron deficiency (ID) in children. Inflammatory cytokine reactions could influence the consequences of H. pylori infection.
Szu-Ta Chen   +3 more
doaj   +1 more source

Hepcidin and sports anemia [PDF]

open access: yesCell & Bioscience, 2014
Iron is an important mineral element used by the body in a variety of metabolic and physiologic processes. These processes are highly active when the body is undergoing physical exercises. Prevalence of exercise-induced iron deficiency anemia (also known as sports anemia) is notably high in athletic populations, particularly those with heavy training ...
Kong, Wei-Na   +2 more
openaire   +2 more sources

The association between Hepcidin and arterial stiffness in a community-dwelling population

open access: yesLipids in Health and Disease, 2018
Background An association of hepcidin with cardiovascular (CV) disease and atherosclerosis has been reported in different patient groups. However, it has not been well described clinically the association between hepcidin and arterial stiffness.
Xiaona Wang   +8 more
doaj   +1 more source

Hepcidin is potential regulator for renin activity

open access: yesPLoS ONE, 2022
An association between genetic variants in the genes HFE, HJV, BMP4 and arterial hypertension has been shown earlier. Proteins encoded by these genes participate in the signalling routes leading eventually to the production of the peptide hormone ...
Jaakko Piesanen   +7 more
doaj   +2 more sources

Sequencing and expression analysis of hepcidin mRNA in donkey (Equus asinus) liver

open access: yesPesquisa Veterinária Brasileira, 2012
The hypoferremia that is observed during systemic inflammatory processes is mediated by hepcidin, which is a peptide that is mainly synthesized in the livers of several mammalian species.
José P. Oliveira-Filho   +6 more
doaj   +1 more source

The effects of a single dialysis session on serum hepcidin levels

open access: yesTürk Biyokimya Dergisi, 2023
Hepcidin plays an important role in regulating iron metabolism. Elevated levels of hepcidin in renal failure contribute to the development of anemia. We aimed to evaluate the association between hepcidin and inflammation in hemodialysis patients and how ...
Oğuzman Hamdi   +3 more
doaj   +1 more source

Biophysical and Cell Biological Studies Characterizing the Vertebrate Iron Exporter Ferroportin [PDF]

open access: yes, 2009
Mammalian iron homeostasis is maintained by an intricate network of diverse proteins that constantly survey systemic iron levels and carefully regulate the uptake of iron from the diet. Control of this uptake is critically important because once iron is
Rice, Adrian Edward
core   +1 more source

Cellular catabolism of the iron-regulatory peptide hormone hepcidin. [PDF]

open access: yesPLoS ONE, 2013
Hepcidin, a 25-amino acid peptide hormone, is the principal regulator of plasma iron concentrations. Hepcidin binding to its receptor, the iron exporter ferroportin, induces ferroportin internalization and degradation, thus blocking iron efflux from ...
Gloria Cuevas Preza   +3 more
doaj   +1 more source

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