Results 41 to 50 of about 25,679 (210)

Kinetic measurements of renin and hepcidin-20 and hepcidin-25.

, 2022
Binding properties of different forms of hepcidin was measured with biolayer interferometry using biotinylated renin as ligand with streptavidin sensors and hepcidin-20 and hepcidin-25 as analyte.
Juha Määttä (12436984), Jarkko Valjakka (197583), Sanna Niemelä (12436978), Jaakko Piesanen (12436975), Seppo Nikkari (530366), Marjut Borgenström (12436981), Tarja Kunnas (530365), Vesa Hytönen (841012)   +7 more
core   +1 more source

Sequencing and expression analysis of hepcidin mRNA in donkey (Equus asinus) liver

Pesquisa Veterinária Brasileira, 2012
The hypoferremia that is observed during systemic inflammatory processes is mediated by hepcidin, which is a peptide that is mainly synthesized in the livers of several mammalian species.
José P. Oliveira-Filho, Jessica A. Marques, Paulo Henrique J. Cunha, Gildenor X. Medeiros, Franklin Riet-Correa, Vânia Maria V. Machado, Alexandre S. Borges   +6 more
doaj   +1 more source

Hepcidin is potential regulator for renin activity

PLoS ONE, 2022
An association between genetic variants in the genes HFE, HJV, BMP4 and arterial hypertension has been shown earlier. Proteins encoded by these genes participate in the signalling routes leading eventually to the production of the peptide hormone ...
Jaakko Piesanen, Jarkko Valjakka, Sanna Niemelä, Marjut Borgenström, Seppo Nikkari, Vesa Hytönen, Juha Määttä, Tarja Kunnas   +7 more
doaj   +2 more sources

The effects of a single dialysis session on serum hepcidin levels

Türk Biyokimya Dergisi, 2023
Hepcidin plays an important role in regulating iron metabolism. Elevated levels of hepcidin in renal failure contribute to the development of anemia. We aimed to evaluate the association between hepcidin and inflammation in hemodialysis patients and how ...
Oğuzman Hamdi, Kın Tekçe Buket, Tekçe Hikmet, Buğdaycı Güler   +3 more
doaj   +1 more source

Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray

ChemFoodChem, EarlyView.
This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi, Adejoke D. Osinubi, Abosede A. Badeji   +2 more
wiley   +1 more source

Anaemia in patients diagnosed with paediatric‐onset inflammatory bowel disease: A Danish nationwide cohort study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Anaemia impairs daily activities and quality of life in patients with paediatric‐onset inflammatory bowel disease (PIBD). This study aimed to investigate the prevalence of anaemia at PIBD‐diagnosis and the following 5 years. Furthermore, anaemia subtypes and the association between anaemia and disease activity were assessed over ...
Julie Rahbek Norup, Sabine Jansson, Vibeke Wewer, Mikkel Malham   +3 more
wiley   +1 more source

Comparison of serum levels of hepcidin and pro-hepcidin in hemodialysis patients and healthy subjects

Saudi Journal of Kidney Diseases and Transplantation, 2015
Hepcidin prevents absorption of iron from the intestine and inhibits release of iron from macrophages and hepatocytes. For this reason, it seems that high levels of hepcidin are a predisposing factor for anemia in chronic inflammatory conditions such as ...
N Taheri, Gh Roshandel, M Mojerloo, M Hadad, H Mirkarimi, R Khorasani Nejad, H R Joshaghani   +6 more
doaj   +1 more source

Hepcidin-25 in chronic hemodialysis patients is related to residual kidney function and not to treatment with erythropoiesis stimulating agents. [PDF]

PLoS ONE, 2012
Hepcidin-25, the bioactive form of hepcidin, is a key regulator of iron homeostasis as it induces internalization and degradation of ferroportin, a cellular iron exporter on enterocytes, macrophages and hepatocytes.
Neelke C van der Weerd, Muriel P C Grooteman, Michiel L Bots, Marinus A van den Dorpel, Claire H den Hoedt, Albert H A Mazairac, Menso J Nubé, E Lars Penne, Carlo A Gaillard, Jack F M Wetzels, Erwin T Wiegerinck, Dorine W Swinkels, Peter J Blankestijn, Piet M Ter Wee, CONTRAST Investigators   +14 more
doaj   +1 more source

Top‐Down CSF Peptidomics Reveals Disease‐Associated Peptide Signatures and Oxidative Modifications in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder

PROTEOMICS, EarlyView.
ABSTRACT Multiple sclerosis and neuromyelitis optica spectrum disorder (NMOSD) are inflammatory demyelinating diseases of the CNS whose diagnosis is mainly based on clinical evidence, magnetic resonance imaging, and the analysis of cerebrospinal fluid (CSF). Current approaches provide only partial insight into disease‐related biological processes, thus
Cristina Contini, Lorena Lorefice, Greca Lai, Alessandra Schirru, Giorgia Zodio, Tiziana Cabras, Alessandra Olianas, Giacomo Diaz, Eleonora Cocco, Barbara Manconi   +9 more
wiley   +1 more source

Hepcidin: Regulation of the master iron regulator [PDF]

, 2015
Iron, an essential nutrient, is required for many diverse biological processes. The absence of a defined pathway to excrete excess iron makes it essential for the body to regulate the amount of iron absorbed; a deficiency could lead to iron deficiency ...
Wallace, Daniel F., Wallace, D.F., Subramaniam, V. Nathan, V. Nathan Subramaniam, Daniel F. Wallace, Gautam Rishi, Rishi, Gautam, Rishi, G., Subramaniam, V.N.   +8 more
core   +1 more source