Results 61 to 70 of about 34,801 (229)

Hepcidin as a risk marker for cardiovascular disease in periodontitis—A case control study

Journal of Indian Academy of Oral Medicine and Radiology, 2023
Background: Hepcidin is a 25 amino acid peptide expressed in the liver. Discovered as late as 2002, hepcidin is a master regulator of iron metabolism and is sensitive to inflammation. Chronic periodontitis, being an inflammatory condition, affects levels
Tejavathi Nagaraj, V S Vaishnavi, Holenarasipur Nagesh Santosh, Durga Okade, Pooja Sinha, J Anitha   +5 more
doaj   +1 more source

Hepcidin Assays [PDF]

Clinical Journal of the American Society of Nephrology, 2009
Iron is the fourth most common element in the earth's crust and the most abundant transition metal in the human body. It is an essential element required for growth and survival. Maintaining the correct iron balance is crucial for health. All living organisms evolved sophisticated mechanisms to maintain appropriate iron levels in their cells and within
openaire   +1 more source

Hepcidin-25 in chronic hemodialysis patients is related to residual kidney function and not to treatment with erythropoiesis stimulating agents. [PDF]

PLoS ONE, 2012
Hepcidin-25, the bioactive form of hepcidin, is a key regulator of iron homeostasis as it induces internalization and degradation of ferroportin, a cellular iron exporter on enterocytes, macrophages and hepatocytes.
Neelke C van der Weerd, Muriel P C Grooteman, Michiel L Bots, Marinus A van den Dorpel, Claire H den Hoedt, Albert H A Mazairac, Menso J Nubé, E Lars Penne, Carlo A Gaillard, Jack F M Wetzels, Erwin T Wiegerinck, Dorine W Swinkels, Peter J Blankestijn, Piet M Ter Wee, CONTRAST Investigators   +14 more
doaj   +1 more source

Comparisons Between Serum Levels of Hepcidin and Leptin in Male College-Level Endurance Runners and Sprinters

Frontiers in Nutrition, 2021
Background: Hepcidin-25 is a 25 amino acid hepatokine and a key regulator of iron metabolism related to iron deficiency anemia. Recent studies have suggested that an elevated hepcidin level is correlated with low energy availability.
Shinsuke Nirengi, Shinsuke Nirengi, Hirokazu Taniguchi, Aya Ishibashi, Mami Fujibayashi, Nao Akiyama, Kazuhiko Kotani, Kazuhiko Kotani, Kengo Ishihara, Naoki Sakane   +9 more
doaj   +1 more source

Immune gene expression profiling of Proliferative Kidney Disease in rainbow trout Oncorhynchus mykiss reveals a dominance of anti-inflammatory, antibody and T helper cell-like activities [PDF]

, 2013
Peer reviewedPublisher ...
Gorgoglione, Bartolomeo, Holland, Jason W, Secombes, Christopher J, Wang, Tiehui   +3 more
core   +2 more sources

Association of HAMP Expression and CD8+ T‐Cell Infiltration With Atezolizumab–Bevacizumab Response in Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
In hepatocellular carcinoma treated with atezolizumab–bevacizumab, responders showed RNA‐seq enrichment of immune and chemokine pathways with higher HAMP expression. In resected specimens, immunohistochemistry confirmed increased intratumoral CD8+ T‐cell density and hepcidin (HAMP), supporting HAMP plus CD8 as components of a composite predictor of ...
Shun Nakamura, Yuki Murakami, Yusuke Oshima, Takashi Masuda, Wataru Miyoshino, Hiroomi Takayama, Yoko Kawano, Teijiro Hirashita, Yuichi Endo, Masafumi Inomata   +9 more
wiley   +1 more source

A tincture of hepcidin cures all: the potential for hepcidin therapeutics [PDF]

Journal of Clinical Investigation, 2010
Iron overload as a result of blood transfusions and excessive intestinal iron absorption can be a complication of chronic anemias such as β-thalassemia. Inappropriately low levels of hepcidin, a negative regulator of iron absorption and recycling, underlie the pathophysiology of the intestinal hyperabsorption. In this issue of the JCI, Gardenghi et al.
Thomas B, Bartnikas, Mark D, Fleming
openaire   +2 more sources

Expression and cellular localization of hepcidin mRNA and protein in normal rat brain [PDF]

, 2016
Background Hepcidin is a peptide hormone belonging to the defensin family of cationic antimicrobial molecules that has an essential role in systemic iron homeostasis.
Raha-Chowdhury, Ruma, Raha, Animesh A, Forostyak, Serhiy, Zhao, Jing-Wei, Stott, Simon, Bomford, Adrian   +5 more
core   +4 more sources

Inflammation and Erythropoietin Resistance in Chronic Kidney Disease: A Cross‐Sectional Study of C‐Reactive Protein and Anemia in Hemodialysis Patients

Journal of Clinical Laboratory Analysis, EarlyView.
This study examined the role of inflammation in anemia among patients with chronic kidney disease on maintenance hemodialysis. Elevated C‐reactive protein (CRP) levels were associated with reduced iron availability, lower hematocrit, and increased erythropoietin requirements.
Collince Odiwuor Ogolla, Lucy W. Karani, Stanslaus Musyoki, Phidelis Maruti   +3 more
wiley   +1 more source

Molecular cloning and expression of novel fibroblast growth factor-2 conjugated with immunodominant domains of pseudomonas exotoxin [PDF]

, 2015
Angiogenesis is very important in cancer growth and metastasis. Basic fibroblast growth factor (bFGF) as one of the most important angiogenesis factors is an attractive target for cancer vaccine.
Farazmandfar, T., Haghighatfard, H., Hakemi, M.G., Jadidi-Niaragh, F., Samaei, N.M., Yamchi, A., Yazdani, Y.   +6 more
core   +1 more source