Results 81 to 90 of about 34,801 (229)
Heme Oxygenase Induction Suppresses Hepatic Hepcidin and Rescues Ferroportin and Ferritin Expression in Obese Mice [PDF]
, 2017 Hepcidin, a phase II reactant secreted by hepatocytes, regulates cellular iron levels by increasing internalization of ferroportin-a transmembrane protein facilitating egress of cellular iron.
Arefiev, Yevgeniy +12 more
core +2 more sources
Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology
Clinical Endocrinology, EarlyView.ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth +7 more
wiley +1 more source
PLoS ONE, 2009 BackgroundHepcidin is a major regulator of iron metabolism and plays a key role in anemia of chronic disease, reducing intestinal iron uptake and release from body iron stores.
Melanie Volke +8 more
doaj +1 more source
Mechanisms of Thrombocytosis in Iron‐Deficiency Anemia
European Journal of Haematology, EarlyView.ABSTRACT Iron‐deficiency anemia is frequently accompanied by reactive thrombocytosis, yet the mechanisms underlying this association remain incompletely understood. Beyond impaired erythropoiesis, iron availability has emerged as an active regulator of hematopoietic lineage decisions.
João Vitor Facco +2 more
wiley +1 more source
Hemojuvelin: The Hepcidin Story Continues [PDF]
Kidney and Blood Pressure Research, 2009 Hemojuvelin (HJV) is a membrane protein that is responsible for the iron overload condition known as juvenile hemochromatosis. HJV, highly expressed in the liver, skeletal muscle and heart, seems to play a role in iron absorption and release from cells and has anti-inflammatory properties.
openaire +2 more sources
Serum hepcidin levels in multiple sclerosis
Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2019 Background Brain iron accumulation is associated with multiple sclerosis (MS). Hepcidin is the master regulator of iron homeostasis and distribution.
Gabriel Bsteh +12 more
doaj +1 more source
The Egyptian Journal of Internal Medicine, 2022 Highlights • Postmenopausal state (PMS) and metabolic syndrome (MetS) are independent factors of high hepcidin. • Estrogen and progesterone are correlated with hepcidin but not explain its higher level in PMS. • Ferritin, insulin resistance, and MetS are
Ragaa Abdelshaheed Matta +3 more
doaj +1 more source
Chronic hyperplastic anemia as an independent risk factor for atherosclerotic lesions: a lesson from thalassemia intermedia [PDF]
, 2010 Introduction. Cardiovascular involvement represents a well-known complication and the primary cause of mortality, both in transfusion-dependent beta thalassemia major (β-TM) and in transfusion-independent beta thalassemia intermedia (β-TI ...
Alessandra Spiga +7 more
core +1 more source
Iron Deficiency in Infancy and Its Impact on Motor and Mental Development [PDF]
, 2020 Iron plays a large role in nerve myelination, dopamine neurotransmission, and neuronal metabolism. The purpose of this literary review was to investigate the connection between iron deficiency and motor and cognitive development.
Baker, Emma
core +1 more source
Haemophilia, EarlyView.ABSTRACT Introduction The National Bleeding Disorder Foundation (NBDF) Medical and Scientific Advisory Council (MASAC) was formed in 1954 and issues recommendations and advisories pertinent to the bleeding disorders community. MASAC is comprised of > 25 rotating members from different medical disciplines and lived experience experts.
Glaivy Batsuli +15 more
wiley +1 more source