Results 81 to 90 of about 30,077 (251)

Kinetic measurements of renin and hepcidin-20 and hepcidin-25.

, 2022
Binding properties of different forms of hepcidin was measured with biolayer interferometry using biotinylated renin as ligand with streptavidin sensors and hepcidin-20 and hepcidin-25 as analyte.
Juha Määttä (12436984), Jarkko Valjakka (197583), Sanna Niemelä (12436978), Jaakko Piesanen (12436975), Seppo Nikkari (530366), Marjut Borgenström (12436981), Tarja Kunnas (530365), Vesa Hytönen (841012)   +7 more
core   +1 more source

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Is Hepcidin a Good Marker for Inflammation in Obstructive Sleep Apnea Syndrome (OSAS) Patients? [PDF]

, 2015
Objective Obstructive Sleep Apnea syndrome (OSAS) is a clinical syndrome characterized by recurrent episodes of upper airway obstruction during sleep, resulting in chronic intermittent hypoxia and causing inflammation. IL-6 and CRP are the most commonly
Ardic, Sadik, Esra Bilgin, Sadik Ardiç, Yuceege, Melike, Faith S. Luyster, Patrick J. Strollo, Cengiz Özdemir, Ahmet U. Demir, Ozdemir, Cengiz, Kizilgun, Murat, Firat, Hikmet, Bilgin, Esra, Luyster, Faith S., Hikmet Firat, Melike Yüceege, Murat Kizilgün   +15 more
core   +1 more source

Subcutaneous Adipose Tissue from Obese and Lean Adults Does Not Release Hepcidin In Vivo

The Scientific World Journal, 2011
Hepcidin is the main regulator of systemic iron homeostasis and is primarily produced by the liver but is also expressed, at the mRNA-level, in periphery tissues including the subcutaneous and visceral adipose tissue.
Lisa Tussing-Humphreys, Keith N. Frayn, Steven R. Smith, Mark Westerman, A. Louise Dennis, Elizabeta Nemeth, Jessica Thomson, Cenk Pusatcioglu   +7 more
doaj   +1 more source

Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities

The Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley   +1 more source

Bacterial Diseases in Farmed Nile Tilapia (Oreochromis niloticus): A Review of Pathogenesis, Immune Responses and Recent Advances in Diagnostics and Management

Aquaculture, Fish and Fisheries, Volume 6, Issue 5, October 2026.
Pathogenesis of bacterial diseases in Nile tilapia and anti‐bacterial mechanisms. ABSTRACT Nile tilapia (Oreochromis niloticus) is among the most widely farmed fish globally that plays a major role in ensuring food security in many low‐ and middle‐income countries.
Catherine Agoe, John Walakira, Gerald Kwikiriza, Nasser Kasozi, Ivan Abaho, Manuel Curto, Paul Meulenbroek, Harald Meimberg, Peter Akoll   +8 more
wiley   +1 more source

Immune cells in the pathogenesis of abdominal aortic aneurysm: Roles, regulation and targeted interventions

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
This review provides a comprehensive overview of how macrophages, neutrophils, T cells and other immune cells infiltrate the aortic wall, undergo phenotypic shifts and interact with one another in abdominal aortic aneurysm (AAA). Background Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease with no approved clinical drugs. Immune
Junqi Peng, Hanqing Zhang, Yun Wu, Song Chen   +3 more
wiley   +1 more source

Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors.

PLoS ONE, 2009
BackgroundHepcidin is a major regulator of iron metabolism and plays a key role in anemia of chronic disease, reducing intestinal iron uptake and release from body iron stores.
Melanie Volke, Daniel P Gale, Ulrike Maegdefrau, Gunnar Schley, Bernd Klanke, Anja-Katrin Bosserhoff, Patrick H Maxwell, Kai-Uwe Eckardt, Christina Warnecke   +8 more
doaj   +1 more source

Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemia

Haematologica, 2007
Hepcidin is the key regulator of systemic iron homeostasis. We describe the modulation of hepcidin production induced by plasma transfusions in a patient with congenital hypotransferrinemia that offers a unique model in which to study the mechanism of ...
Paola Trombini, Tiziana Coliva, Elizabeta Nemeth, Raffaella Mariani, Tomas Ganz, Andrea Biondi, Alberto Piperno   +6 more
doaj   +1 more source

Bioactive peptides in cancer and inflammation: Mechanisms, model systems and clinical translation

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Bioactive peptides (BAPs) derived from host, marine, insect, plant and synthetic sources share cationic, amphipathic structures adopting α‐helical, β‐sheet or cyclic conformations. These features underlie anti‐cancer effects, including membrane disruption, apoptosis and cell‐cycle arrest, anti‐metastatic activity, reduced invasion and migration, and ...
Najwa Doha, Richa Gill, Sergio Crovella, Haissam Abou‐Saleh, Sahar Isa Da'as   +4 more
wiley   +1 more source