Results 91 to 100 of about 25,679 (210)

Serum hepcidin levels in multiple sclerosis

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2019
Background Brain iron accumulation is associated with multiple sclerosis (MS). Hepcidin is the master regulator of iron homeostasis and distribution.
Gabriel Bsteh, David Haschka, Piotr Tymoszuk, Klaus Berek, Verena Petzer, Harald Hegen, Sebastian Wurth, Michael Auer, Anne Zinganell, Franziska Di Pauli, Florian Deisenhammer, Guenter Weiss, Thomas Berger   +12 more
doaj   +1 more source

A MUC13 Variant Enhances Intestinal Ferric Iron Absorption in Unexplained Hyperferritinemia

Liver International, Volume 46, Issue 11, November 2026.
ABSTRACT Background & Aims Hyperferritinemia frequently remains unexplained despite comprehensive evaluation. We conducted a sequencing‐based exome association study to identify genetic variants associated with plasma ferritin levels in patients with unexplained hyperferritinemia.
Jonas Callet, Yong H. Sheng, Yaowu He, Maël Silva Rodriguez, Céline Chéry, Ramia Safar, Françoise Barbé, Mouni Bensenane, Rosa‐Maria Guéant‐Rodriguez, Fares Namour, Guillaume Gauchotte, Janelle Louise Hancock, Hana Manceau, Thibaud Lefebvre, Dimitri Tchernitchko, Hervé Puy, Timothy H. Florin, Jakob Begun, John D. Hooper, Jean‐Pierre Bronowicki, Michael A. McGuckin, Jean‐Louis Guéant, Abderrahim Oussalah   +22 more
wiley   +1 more source

Hepcidin in β‐thalassemia [PDF]

Annals of the New York Academy of Sciences, 2010
Iron overload is the principal cause of morbidity and mortality in β‐thalassemia with or without transfusion dependence. Iron homeostasis is regulated by the hepatic peptide hormone hepcidin. Hepcidin controls dietary iron absorption, plasma iron concentrations, and tissue iron distribution.
openaire   +2 more sources

Expression of hepcidin mRNA is uniformly suppressed in hepatocellular carcinoma

BMC Cancer, 2008
Background The present study evaluated the expression of hepcidin mRNA in hepatocellular carcinoma (HCC). Methods Samples of cancerous and non-cancerous liver tissue were taken from 40 patients with HCC who underwent hepatectomy.
Tomosugi Naohisa, Sawada Tokihiko, Kijima Hiroaki, Kubota Keiichi   +3 more
doaj   +1 more source

Gestational Changes in Placental Iron Homeostasis are Associated With Ferroptosis‐Associated Redox Signaling and Trophoblast Behavior

The FASEB Journal, Volume 40, Issue 19, 15 October 2026.
This graphical abstract summarizes gestational changes in placental iron homeostasis and their relationship to ferroptosis‐associated molecular features. In trophoblast cells, experimentally induced sublethal iron‐dependent redox perturbation modulates migration and invasion without causing overt ferroptotic cell death, whereas iron chelation or ...
Wenxin Jiang, Yike Yang, Xiao Yuan, Wei Deng, Mark D. Kilby, Philip N. Baker, Chao Tong, Yi Yang   +7 more
wiley   +1 more source

Hepcidin-mediated Fpn control and inhibition of Fpn transcription contribute to the acute inflammatory response.

, 2017
A-Experimental data (means with standard deviation) and simulated data (lines) for serum iron content following peritoneal injection of LPS for mice maintained on a standard or iron-enriched diet.
Mihaela Enculescu (3626096), Maximilian Hahnel (3626093), Stefan Legewie (65841), Martina U. Muckenthaler (156534), Johannes Bode (3424313), Christoph Metzendorf (3626090), Richard Sparla (3626087)   +6 more
core   +1 more source

Obesity‐Related Inflammation Masks Iron Deficiency in US Women

American Journal of Hematology, Volume 101, Issue 12, Page 3043-3046, December 2026.
Sixtus Aguree, Sai Chakrri Tadikonda
wiley   +1 more source

Modelling of a metal-containing hepcidin

, 2006
Hepcidin was originally identified as a liver-expressed antimicrobial peptide but further studies have shown that it also has a key role in iron homeostasis.
Evans, Robert, Evans, R.W., Farnaud, S., Patel, A.   +3 more
core   +1 more source

Hepcidin level predicts hemoglobin concentration in individuals undergoing repeated phlebotomy

Haematologica, 2013
Dietary iron absorption is regulated by hepcidin, an iron regulatory protein produced by the liver. Hepcidin production is regulated by iron stores, erythropoiesis and inflammation, but its physiology when repeated blood loss occurs has not been ...
Alan E. Mast, Karen S. Schlumpf, David J. Wright, Bryce Johnson, Simone A. Glynn, Michael P. Busch, Gordana Olbina, Mark Westerman, Elizabeta Nemeth, Tomas Ganz   +9 more
doaj   +1 more source

Quantification of hepcidin isoforms using hepcidin-25⁺⁴⁰ as internal standard.

, 2013
A. Linearity (range 0–40 nM) for hepcidin-25, hepcidin-24, hepcidin-22, and hepcidin-20 as determined by hepcidin-25+40 as internal standard. Linearity curves are assessed in different runs. Blank serum (hep-24, hep-20 and hep-25) or heparin plasma (used
Hendrik Gille (466748), Dorine W. Swinkels (90370), Andreas M. Hohlbaum (226312), Coby M. M. Laarakkers (228091), Harold Tjalsma (90375), Siem Klaver (466746), Maria Kolodziejczyk (466747), Erwin T. Wiegerinck (151361)   +7 more
core   +1 more source