Results 111 to 120 of about 34,801 (229)

Comparative Analysis of Potential Side Effects of Targeted Oral Hypoglycemic Agents Using Spontaneous Adverse Event Reports and Social Media Data

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Aim Adverse events (AEs) detected in tweets and in the FDA Adverse Event Reporting System (FAERS) provide valuable insights into patient experiences with oral hypoglycemic agents including sodium‐glucose transporter 2 (SGLT2) and dipeptidyl peptidase‐4 (DPP4) inhibitors. This study compared the side effects identified from tweets with those in
Se‐Hoon Oh, Dong‐Young Park, Yun‐Kyoung Song   +2 more
wiley   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source

Lactoferrin efficiently counteracts the inflammation-induced changes of the iron homeostasis system in macrophages [PDF]

, 2017
Human lactoferrin (hLf), an 80-kDa multifunctional iron-binding cationic glycoprotein, is constitutively secreted by exocrine glands and by neutrophils during inflammation. hLf is recognized as a key element in the host immune defense system.
Aisen, Andrews, Baker, Barber, Cairo, Corna, Cutone, De Domenico, Donovan, Frazer, Frioni, Ganz, Ganz, Genin, Legrand, Mackenzie, Mazumder, Miller, Musci, Paesano, Paesano, Paesano, Paesano, Park, Puddu, Puddu, Recalcati, Ross, Scorneaux, Theil, Valenti, Ward   +31 more
core   +2 more sources

Growth Differentiation Factor‐15 Could Predict Decreased Hemoglobin in Tuberculosis Treated With Linezolid‐Containing Regimen

The Clinical Respiratory Journal, Volume 20, Issue 5, May 2026.
Baseline GDF‐15 predicts linezolid‐induced myelosuppression in rifampicin‐resistant tuberculosis. Patients with higher pretreatment GDF‐15 (> 950 pg/mL) were more likely to develop significant hemoglobin decline during therapy. Measuring GDF‐15 before treatment may help identify high‐risk patients and guide safer, personalized linezolid use.
Amaylia Oehadian, Prayudi Santoso, Delita Prihatni, Andini Kartikasari, Ida Parwati, Diah Handayani, Thomas Handoyo, Noorwati Sutandiyo, Bachti Alisjahbana, Dick Menzies, Rovina Ruslami   +10 more
wiley   +1 more source

Inflammatory responses in primary muscle cell cultures in Atlantic salmon (Salmo salar) [PDF]

, 2013
Peer reviewedPublisher ...
Martin, Samuel A.M., Pooley, Nicholas J., Secombes, Christopher J., Tacchi, Luca   +3 more
core   +2 more sources

Identification of Common Blood Metabolic Derangements Using Magnetic Resonance Signatures of the Pancreas and Liver

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4162-4175, May 2026.
ABSTRACT Aim To investigate whether common disturbances of glucose and lipid metabolism can be automatically identified from magnetic resonance signatures of the pancreas and liver. Methods In this proof‐of‐principle study, 100 individuals with a history of pancreatitis—a relatively homogeneous population at risk for metabolic derangements—underwent ...
Wandia Kimita, Juyeon Ko, Loren Skudder‐Hill, Xiatiguli Shamaitijiang, Yutong Liu, Maxim S. Petrov   +5 more
wiley   +1 more source

Evolution of Th2 responses : Characterization of IL-4/13 in sea bass (Dicentrarchus labrax L.) and studies of expression and biological activity [PDF]

, 2017
Acknowledgements This research was funded by the European Commission under the 7th Framework Programme for Research and Technological Development (FP7) of the European Union (Grant Agreement 311993 TARGETFISH). T.W.
A Antczak, A Bhattacharjee, A Munitz, AE Lockyer, E Wangkahart, EJ Song, F Buonocore, F Takizawa, G Biswas, G Scapigliati, H Nielsen, J Zhu, J Zou, JE Allen, JH Li, JW Hodgkinson, K Bao, K Tamura, L-y Zhu, LM Braden, M Howard, M Ohtani, M Tine, M Wills-Karp, MG Reese, MM Costa, MO Huising, N Nunez Ortiz, PJ Lupardus, RC Edgar, RL Coffman, S Almeria, S Kumar, S McCormick, SP Gadani, T Hage, T Maehr, T Wang, T Wang, T Wang, T Wang, T Yamaguchi, T Yamaguchi, TA Wynn, TA Wynn   +44 more
core   +1 more source

Iron Status, Erythropoietin, and Cancer Incidence in the General Population

European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
This study investigated the association between iron parameters and EPO and the development of overall and site‐specific cancer in a large cohort with a median follow‐up of 18.5 years (n = 6109; 1090 de novo malignancies). In multivariable cox proportional hazard analysis, we found that increased EPO, and decreased hepcidin concentrations are ...
Siem J. van Alfen, Pien Rawee, Li Luo, Ilja M. Nolte, Bert van der Vegt, Jenny E. Kootstra‐Ros, Stephan J. L. Bakker, Ron T. Gansevoort, Thera P. Links, Wouter T. Zandee, Michele F. Eisenga   +10 more
wiley   +1 more source

Functional analyses of recombinant mouse hepcidin-1 in cell culture and animal model

, 2013
Hepcidin is a peptide hormone that plays an important role in iron metabolism. We have produced a recombinant mouse hepcidin-1 by using baculovirus expression system.
Kalhor, H.R., Keyhanvar, N., Rezaei, A., Yazdani, Y.   +3 more
core   +1 more source

Silencing airway epithelial cell-derived hepcidin exacerbates sepsis-induced acute lung injury [PDF]

, 2014
INTRODUCTION: The production of antimicrobial peptides by airway epithelial cells is an important component of the innate immune response to pulmonary infection and inflammation. Hepcidin is a β-defensin-like antimicrobial peptide and acts as a principal
Cong Li Zeng, Jun Lu Wang, Qi Xing Chen, Qing Hua Chen, Sheng Wen Song, Xia Zheng, Xiang Ming Fang   +6 more
core   +1 more source