Results 121 to 130 of about 34,801 (229)

Single‐Cell Analysis of Preeclamptic Cord Blood Mononuclear Cells Revealed Activation of Heme‐Associated Signalling Pathways

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Preeclampsia is a severe gestational complication whose molecular pathogenesis remains poorly understood despite extensive research. It is now recognized that both maternal and fetal cells contribute to disease progression. Notably, single‐cell RNA sequencing of cord blood cells from preeclamptic pregnancies has not been previously ...
Polina Vishnyakova, Evgeny Karpulevich, Victoria Karyagina, Elena Gantsova, Yulia Trofimovich, Viktoriia Kiseleva, Miroslava Chirkova, Tatiana Gerashchenko, Anastasiya Lokhonina, Kamilla Muminova, Zulfiya Khodzhaeva, Evgeny Denisov, Andrey Elchaninov, Timur Fatkhudinov, Gennady Sukhikh   +14 more
wiley   +1 more source

Clinical Exome Sequencing in Unexplained Hyperferritinemia Reveals Digenic and Oligogenic Inheritance Beyond Iron Homeostasis

Liver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background and Aims Hyperferritinemia encompasses heterogeneous genetic etiologies beyond HFE‐related hemochromatosis. Current guidelines recommend testing for rare hemochromatosis genes, yet no consensus exists on comprehensive genomic approaches.
Paul Morel, Maël Silva Rodriguez, Cyriaque Benmouffek, Betul Goksen, Céline Chéry, Vincent Haghnejad, Mouni Bensenane, François Feillet, Jean‐Louis Guéant, Farès Namour, Jean‐Pierre Bronowicki, Abderrahim Oussalah   +11 more
wiley   +1 more source

What regulates hepcidin in poly-transfused β-Thalassemia Major: Erythroid drive or store drive?

Indian Journal of Pathology and Microbiology, 2014
Background: Hepcidin, a key regulator of iron homeostasis, is increased by iron overload and inflammation while suppressed by hypoxia. In spite of iron overload in β-Thalassemia Major (β-TM), a paradoxical decrease in hepcidin is observed. Aim: To assess
Richa Chauhan, Sunita Sharma, Jagdish Chandra   +2 more
doaj   +1 more source

Adverse Prognostic Impact of Pretransplant Serum Ferritin and Hepcidin on Survival Outcomes After Allogeneic Hematopoietic Stem Cell Transplantation

American Journal of Hematology, Volume 101, Issue 6, Page 1239-1243, June 2026.
Michelle Pirotte, Marianne Fillet, Laurence Seidel, Evelyne Willems, Sophie Servais, Fréderic Baron, Yves Beguin   +6 more
wiley   +1 more source

Reduced hepcidin level features osteoporosis

Experimental and Therapeutic Medicine, 2018
Osteoporosis (OP) is a common serious skeletal disorder marked by increased risk of bone fracture due to fragility. OP has been taken to be a disease linked with abnormal calcium metabolism that alone is obviously insufficient to explain the development of OP.
Liu, Bin, Liu, Caihua, Zhong, Weifeng, Song, Min, Du, Shouqin, Su, Jianli   +5 more
openaire   +3 more sources

Serum Hepcidin-25: A Predictor Of Response To Oral Iron Therapy.

Pakistan Journal of Medicine and Dentistry
Background: Discovery of hepcidin, and its receptor in year 2000 has revolutionized iron metabolism studies. Measurement of serum hepcidin, may supplement existing investigational parameters of iron status in anemias.
Ghazala Masood Farrukh, Adnan Zubairi, Amal Kamal, Syed Tauseef Ahmed   +3 more
doaj  

Hepcidin Plays a Key Role in 6-OHDA Induced Iron Overload and Apoptotic Cell Death in a Cell Culture Model of Parkinson’s Disease

Parkinson's Disease, 2016
Background. Elevated brain iron levels have been implicated in the pathogenesis of Parkinson’s disease (PD). However, the precise mechanism underlying abnormal iron accumulation in PD is not clear.
Qi Xu, Anumantha G. Kanthasamy, Huajun Jin, Manju B. Reddy   +3 more
doaj   +1 more source

The effect of blood transfusion on serum hepcidin levels in chronically transfused patients of β-thalassemia major: An observational study in a tertiary care centre in Western Maharashtra

Asian Journal of Transfusion Science
INTRODUCTION: Hepcidin is the key regulator of systemic iron homeostasis. In iron-loading anemias, hepcidin levels are regulated by opposite forces of erythropoiesis and iron overload.
Sujay Bhowmik, Amit Kumar Biswas, Ajay Kumar Baranwal, Amit Ajay Pawar, Ujjwal Dimri   +4 more
doaj   +1 more source

The effects of morning preconditioning protocols on testosterone, cortisol and afternoon sprint cycling performance [conference presentation] [PDF]

, 2018
Opportunities exist for athletes to undertake morning exercise protocols in an attempt to potentate afternoon performance. Four sub elite track sprint cyclists completed a morning cycling (Cyc) or weights-based protocol (WP) prior to an afternoon cycling
Maulder, Peter S, McDonald, Kerin
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GPS analysis of a team competing at a national Under 18 field hockey tournament [PDF]

, 2018
The purpose of this study was to utilise global-positioning system (GPS) technology to quantify the running demands of national Under 18 field hockey players competing in a regional field hockey tournament.
Van der Merwe, Frans H
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