Hepcidin Exacerbates Iron Metabolism Imbalance in Septic Mice [PDF]
Liyan Wu,1 Zhenyan Yuan,1 Min Wang,1 Xiaomeng Fu,1 Xiaohui Liu,1 Bing Wei,2 Yugeng Liu1 1Department of Infectious Diseases and Clinical Microbiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100043, People’s Republic of China ...
Wang M +6 more
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The serum hepcidin and the hepcidin/ferritin ratio in NAFLD: a systematic review and meta-analysis
BMC GastroenterologyBackground Non-alcoholic fatty liver disease (NAFLD) is a spectrum of chronic liver diseases characterized by hepatic steatosis exceeding 5% in the absence of alcohol and other liver-damaging factors.
Jingmin Song +7 more
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Positive hepcidin/pro-hepcidin staining in ischemic brain.
, 2013 Hepcidin/pro-hepcidin was detected by immunohistochemistry. Hepcidin/pro-hepcidin positive staining was significantly increased in cerebral cortex, hippocampus and corpus striatum of ischemic brain.
Ya-Shuo Zhao (343734) +9 more
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L (2011) Molecular mechanisms regulating hepcidin revealed by hepcidin disorders
, 2020 Iron is essential for human life, but toxic if present in excess. To avoid iron overload and maintain iron homeostasis, all cells are able to regulate their iron content through the post-transcriptional control of iron genes operated by the cytosolic ...
Clara Camaschella, Laura Silvestri
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Kupffer cells modulate iron homeostasis in mice via regulation of hepcidin expression
, 2007 Hepcidin, a small cationic liver derived peptide, is a master regulator of body iron homeostasis. Cytokines and iron availability have so far been identified as regulators of hepcidin expression.
Hochegger, Kathrin +16 more
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Ferritin Normalization Is Not Disease Control in HFE ‐Related Hemochromatosis: Residual Risk, Transferrin Saturation, and the Hepcidin–Ferroportin Axis [PDF]
Naga Praneeth Raja
openalex +1 more source
Hepcidin peptide treatment induces intracellular hepcidin expression.
, 2013 Huh7.5 cells were incubated with hepcidin for 0.5 h, 1 h and 4 h, followed by total RNA extraction. QRT-PCR was performed to examine hepcidin mRNA expression. The data are presented as mean ± SD from three independent experiments.
Robertson Keith (302087) +5 more
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Production of Recombinant Bacmid Containing the Coding Sequence of Human Hepcidin
Medical Laboratory Journal, 2013 Background and objective: Hepcidin is a cystein-rich antimicrobial peptide, which is secreted by the liver. It fights against wide spectrum of bacteria, viruses and fungi and it is a major regulator of iron homeostasis.
N Keyhanvar, A Tabarraei, Y Yazdani
doaj
Hepcidin Regulation of Iron Transport
, 2008 The discovery of hepcidin as a key regulator of iron homeostasis has advanced our current knowledge of this field. Liver-derived hepcidin peptide is secreted in response to iron and inflammation and interacts with the iron export protein ferroportin ...
Collins, James F. +5 more
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Chronic hyperplastic anemia as an independent risk factor for atherosclerotic lesions: a lesson from thalassemia intermedia [PDF]
, 2010 Introduction. Cardiovascular involvement represents a well-known complication and the primary cause of mortality, both in transfusion-dependent beta thalassemia major (β-TM) and in transfusion-independent beta thalassemia intermedia (β-TI ...
Pier Luigi Cocco +7 more
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