Results 101 to 110 of about 25,679 (210)

Validation of hepcidin quantification in plasma using LC-HRMS and discovery of a new hepcidin isoform.

, 2013
BACKGROUND: Hepcidin, a 25 amino acid peptide, plays an important role in iron homeostasis. Some hepcidin truncated peptides have antibiotic effects. RESULTS: A new analytical method for hepcidin determination in human plasma using LC-HRMS operating in ...
Waldvogel, S., McMullen, J., Bromirski, M., Peduzzi, D., Kottelat, E., Rochat, B., Angelillo-Scherrer, A., Favrat, B., Favre, A., Tissot, J.D., Favre A, Waldvogel S, Kottelat E, Tissot JD, Favrat B, Angelillo-Scherrer A, Bromirski M, Peduzzi D, Rochat B, McMullen J   +19 more
core   +1 more source

Hemojuvelin: The Hepcidin Story Continues [PDF]

Kidney and Blood Pressure Research, 2009
Hemojuvelin (HJV) is a membrane protein that is responsible for the iron overload condition known as juvenile hemochromatosis. HJV, highly expressed in the liver, skeletal muscle and heart, seems to play a role in iron absorption and release from cells and has anti-inflammatory properties.
openaire   +2 more sources

TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals.

, 2011
The iron hormone hepcidin is inhibited by matriptase-2, a liver serine-protease encoded by TMPRSS6 gene. Cleaving the BMP-coreceptor hemojuvelin, matriptase-2 impairs the BMP/SMAD signaling pathway, downregulates hepcidin and facilitates iron ...
GIRELLI, Domenico, Camaschella C., CAMPOSTRINI, Natascia, Nai A., Traglia M., Silvestri L., Pagani A., Toniolo D., CORBELLA, Michela   +8 more
core   +3 more sources

RETRACTED: The Role of Ubiquitination in Hepcidin-Independent and Hepcidin-Dependent Degradation of Ferroportin

Cell Metabolism, 2011
The iron exporter ferroportin (Fpn) is essential to transfer iron from cells to plasma. Systemic iron homeostasis in vertebrates is regulated by the hepcidin-mediated internalization of Fpn. Here, we demonstrate a second route for Fpn internalization; when cytosolic iron levels are low, Fpn is internalized in a hepcidin-independent manner dependent ...
De Domenico, Ivana, Lo, Eric, Yang, Baoli, Korolnek, Tamara, Hamza, Iqbal, Ward, Diane McVey, Kaplan, Jerry   +6 more
openaire   +2 more sources

Hepcidin Expression in Psoriasis Patients

Indian Journal of Dermatology, 2014
Background: Iron is an essential nutrient for mammals. Accelerated loss of nutrients through hyperproliferation and desquamation from the skin in psoriasis is known. Hepcidin is an important and recently discovered regulator of iron homeostasis.
Nursel Dilek, Aziz Ramazan Dilek, Kazim Şahin, Neşe Kaklikkaya, Yunus Saral   +4 more
openaire   +3 more sources

Correlations between liver hepcidin mRNA, serum hepcidin, ferritin and clinical characteristics of patients.

, 2015
NA: not applicable.Correlations between liver hepcidin mRNA, serum hepcidin, ferritin and clinical characteristics of patients.
Asterios Saitis (782944), Aggeliki Lyberopoulou (486475), Eleni Kyratzopoulou (782943), George Simos (313798), Nikolaos K. Gatselis (782942), George K. Koukoulis (782946), Petros Eliades (782945), Georgia Chachami (313797), Efrosini Paraskeva (288856), Avgi Mamalaki (325291), Kalliopi Zachou (33150), George N. Dalekos (782947), Stella Gabeta (33156)   +12 more
core   +1 more source

Similarity and identity scores based on the deduced peptides of all currently known hybrid striped bass piscidins, Larimichthys crocea hepcidin (Lc Hepcidin; GenBank assession EU443735), and Monopterus albus hepcidin (Ma Hepcidin; GenBank assession GU997139).

, 2016
Similarity and identity scores based on the deduced peptides of all currently known hybrid striped bass piscidins, Larimichthys crocea hepcidin (Lc Hepcidin; GenBank assession EU443735), and Monopterus albus hepcidin (Ma Hepcidin; GenBank assession ...
Benjamin J. Reading (562669), Edward J. Noga (3072090), Katherine R. Cassady (3072087), Scott A. Salger (3072093)   +3 more
core   +1 more source

Hepcidin and Cytokines in Anaemia

Hematology, 2004
Hepcidin is a cytokine-induced antibacterial protein which is produced in the liver, circulates in the blood, and is excreted in the urine. It is a major regulator of iron balance in the intestinal mucosa, and appears to have a significant role in the pathogenesis of haemochromatosis and related disorders.
openaire   +2 more sources

Hepcidin Exacerbates Iron Metabolism Imbalance in Septic Mice [PDF]

Liyan Wu,1 Zhenyan Yuan,1 Min Wang,1 Xiaomeng Fu,1 Xiaohui Liu,1 Bing Wei,2 Yugeng Liu1 1Department of Infectious Diseases and Clinical Microbiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100043, People’s Republic of China ...
Wang M, Liu X, Liu Y, Wu L, Wei B, Fu X, Yuan Z   +6 more
core  

Hepcidin Plays a Key Role in 6-OHDA Induced Iron Overload and Apoptotic Cell Death in a Cell Culture Model of Parkinson’s Disease

Parkinson's Disease, 2016
Background. Elevated brain iron levels have been implicated in the pathogenesis of Parkinson’s disease (PD). However, the precise mechanism underlying abnormal iron accumulation in PD is not clear.
Qi Xu, Anumantha G. Kanthasamy, Huajun Jin, Manju B. Reddy   +3 more
doaj   +1 more source