Results 231 to 240 of about 121,405 (297)

Iron Overload Cardiomyopathy in Myelodysplastic Syndrome: A Fatal Outcome After 20 Years of Chronic Transfusions. [PDF]

JACC Case Rep
Hayashida M, Nohara S, Yamakawa R, Nishikido A, Matsushima Y, Yanai T, Ishimatsu T, Otsuka M, Fukumoto Y.   +8 more
europepmc   +1 more source

Dual targeting of BRAF^V600E and ferroptosis results in synergistic anticancer activity via iron overload and enhanced oxidative stress. [PDF]

J Exp Clin Cancer Res
Hu J, Ghosh C, Khaket TP, Yang Z, Tabdili Y, Alamaw ED, Boufraqech M, Dixon SJ, Kebebew E.   +8 more
europepmc   +1 more source

Dose‐dependent impairment of brain functional and microstructural connectivity during leukaemia chemotherapy

British Journal of Haematology, EarlyView.
Prospective functional MRI brain and neurocognitive assessments were performed serially during intensive chemotherapy for a cohort of adults with newly diagnosed acute myeloid leukaemia to elucidate ‘chemobrain’ language phenomena. At completion of consolidation, significant reductions in functional and microstructural connectivity were observed ...
Ashleigh P. Scott, Ada Lo, Ying Xia, Kate Thompson, Harriet Bodimeade, Amir Fazlollahi, Nicholas Weber, Cameron Curley, Stewart Hunt, Kirk Morris, Caroline McNamara, Nilu Perera, Elango Subramoniapillai, Steven W. Lane, Glen A. Kennedy, Olivier Salvado, Javier Urriola, Katie L. McMahon   +17 more
wiley   +1 more source

Iron overload-induced ferroptosis in CD8⁺ T cells leads to functional abnormalities that promote endometriosis progression. [PDF]

BMC Med
Wang S, Xu L, Jiao X, Dong X, Zhong Z, Ren Q, Liu X, Yuan M, Wang G.   +8 more
europepmc   +1 more source

Polychlorinated Biphenyl 138 Induces Toxicant-Associated Steatohepatitis via Hepatic Iron Overload and Adipose Inflammation. [PDF]

Toxics
Hwang HJ, Lee MH, Lee SH, Sung BJ, Kim JG, Seo DY, Hur DY, Yoo YH, Cheong J, Kim HY.   +9 more
europepmc   +1 more source

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu, Xingju Zou, Yang Zheng, Chen Sun, Cheng Peng   +4 more
wiley   +1 more source

A Case Series on Beta Thalassemia Major With Secondary Diabetes Mellitus Due to Iron Overload and Other Complications. [PDF]

Cureus
Sahu UP, Rani N, Hasan O, Mobin N, Singh PK, Soumya S, Rajak PK, Kumar N.   +7 more
europepmc   +1 more source

LCN2‐ACOD1 Signalling Affects the Post‐Injury Regeneration of Skeletal Muscle Through Mediating Ferroptosis

Cell Proliferation, EarlyView.
LCN2 mediates the suppression of C2C12 myoblast proliferation and myotube formation via erastin‐induced ferroptosis. Mechanistically, the LCN2‐ACOD1 axis regulates skeletal muscle growth via mitochondria‐associated ferroptosis, providing a theoretical basis for the prevention and therapy of muscle‐related diseases.
Xiaojing Hao, Hongwei Shi, Di Wu, Rui Liang, Tong Zhao, Wen Sun, Yue Wang, Xiuju Yu, Xiaomao Luo, Yi Yan, Jiayin Lu, Haidong Wang, Juan Wang   +12 more
wiley   +1 more source

Iron Overload and Its Impact on Liver Function and Lipid Profiles in Transfusion-Dependent β-Thalassemia Patients in Sana'a City. [PDF]

J Blood Med
Al-Shami A, Alzomor M.
europepmc   +1 more source