Results 81 to 90 of about 53,613 (303)

Association of HAMP Expression and CD8+ T‐Cell Infiltration With Atezolizumab–Bevacizumab Response in Hepatocellular Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
In hepatocellular carcinoma treated with atezolizumab–bevacizumab, responders showed RNA‐seq enrichment of immune and chemokine pathways with higher HAMP expression. In resected specimens, immunohistochemistry confirmed increased intratumoral CD8+ T‐cell density and hepcidin (HAMP), supporting HAMP plus CD8 as components of a composite predictor of ...
Shun Nakamura   +9 more
wiley   +1 more source

Parents' WhatsApp coping resources in the context of ongoing political conflicts: An ecological exploration

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract Mobile technologies have become significant resources for crisis communication and social support in recent years. However, despite empirical evidence pointing to the centrality of these technologies for parenthood in everyday life, it is yet unknown how parents' coping resources play a role in the digital environment.
Daphna Yeshua‐Katz   +2 more
wiley   +1 more source

Iron Metabolism in Patients with Paroxysmal Nocturnal Hemoglobinuria: Results of a Single-Center Ambispective Clinical Trial

open access: yesКлиническая онкогематология
BACKGROUND. Paroxysmal nocturnal hemoglobinuria (PNH) is a rare clonal hematologic disease manifesting among others in hemolytic anemia. Due to predominantly intravascular hemolysis, iron metabolism in PNH patients is characterized by a number of ...
Vitalii Dmitrievich Latyshev   +5 more
doaj   +1 more source

The transplant iron score as a predictor of stem cell transplant survival

open access: yesJournal of Hematology & Oncology, 2009
Recent studies have suggested that the presence of iron overload prior to stem cell transplantation is associated with decreased survival. Within these studies, the criteria used to define iron overload have varied considerably.
Keung Yi K   +10 more
doaj   +1 more source

Impact of Mutational Landscape and Burden on RBC Transfusion Response in Patients With Lower‐Risk Myelodysplastic Syndromes (LR‐MDS) in the COMMANDS Study

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT The COMMANDS trial established luspatercept as a first‐line treatment for anemia in transfusion‐dependent lower‐risk (LR) myelodysplastic syndromes (MDS). Here we report red blood cell (RBC) transfusion response analysis based on somatic mutations profile and disease risk for patients treated with luspatercept or epoetin alfa in the COMMANDS ...
Rami S. Komrokji   +9 more
wiley   +1 more source

Mycobacterium avium Complex Infection in a Patient with Sickle Cell Disease and Severe Iron Overload

open access: yesCase Reports in Infectious Diseases, 2014
A 34-year-old female with sickle cell anemia (hemoglobin SS disease) and severe iron overload presented to our institution with the subacute presentation of recurrent pain crisis, fever of unknown origin, pancytopenia, and weight loss.
Kamal Shemisa   +4 more
doaj   +1 more source

Carrier-Free Deferoxamine Nanoparticles against Iron Overload in Brain

open access: diamond, 2022
Fang Zhu   +7 more
openalex   +1 more source

Severe Iron Overload [PDF]

open access: yesClinical Gastroenterology and Hepatology, 2019
Manhal Izzy, Patrick S. Kamath
openaire   +2 more sources

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