Results 81 to 90 of about 1,130,858 (355)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Low-Temperature Clay Mineral Dehydration Contributes to Porewater Dilution in Bering Sea Slope Subseafloor

open access: yesFrontiers in Earth Science, 2018
Widespread diagenesis of clay minerals occurs in deeply buried marine sediments under high-temperature and high-pressure conditions. For example, the smectite-to-illite (S-I) transformation has been often observed in sediments at in situ temperatures ...
Akira Ijiri   +12 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Enzymatic Reduction of Iron Oxide by Fungi [PDF]

open access: yesApplied Microbiology, 1969
The occurrence of the iron-reducing phenomenon among some common fungi was studied. Results indicated that (i) the reduction of ferric iron to the ferrous state by fungi seems to be restricted to nitrate reductase-inducible strains such as Actinomucor repens, Alternaria tenuis, Fusarium oxysporum , and F.
J C, Ottow, A, Von Klopotek
openaire   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

A Conceptual Model for Depicting the Relationships between Toluene Degradation and Fe(III) Reduction with Different Fe(III) Phases as Terminal Electron Acceptors

open access: yesApplied Sciences
Iron reduction is one of the most crucial biogeochemical processes in groundwater for organic contaminants biodegradation, especially in the iron-rich aquifers.
He Di   +5 more
doaj   +1 more source

Insights into secondary reactions occurring during atmospheric ablation of micrometeoroids [PDF]

open access: yes, 2016
Ablation of micrometeoroids during atmospheric entry yields volatile gases such as water, carbon dioxide, and sulfur dioxide, capable of altering atmospheric chemistry and hence the climate and habitability of the planetary surface.
Court, RW, Tan, J
core   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Highly Diverse Aquatic Microbial Communities Separated by Permafrost in Greenland Show Distinct Features According to Environmental Niches

open access: yesFrontiers in Microbiology, 2019
The Greenland Analog Project (GAP) study area in the vicinity of Kangarlussuaq, Western Greenland, was sampled for surface water and deep groundwater in order to determine the composition and estimate the metabolic features of the microbial communities ...
Malin Bomberg   +3 more
doaj   +1 more source

Enhancing properties of iron and manganese ores as oxygen carriers for chemical looping processes by dry impregnation [PDF]

open access: yes, 2015
The use of naturally occurring ores as oxygen carriers in CLC processes is attractive because of their relative abundance and low cost. Unfortunately, they typically exhibit lower reactivity and lack the mechanical robustness required, when compared to ...
Anthony, Edward J.   +8 more
core   +1 more source

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