Results 41 to 50 of about 46,543 (267)

Australian Practitioners' Beliefs, Confidence, and Training Needs for Delivering Behaviour Support to Children and Young People in Out‐of‐Home Care

open access: yesAustralian Journal of Social Issues, EarlyView.
ABSTRACT Children in out‐of‐home care (OOHC) frequently present with complex behavioural needs. In New South Wales (NSW), behaviour support plans (BSPs) are mandated when restrictive practices, including psychotropic medication, are used. Little research has examined whether the statutory workforce is adequately prepared to meet behaviour support ...
Manisha Abayakoon Stanborough   +4 more
wiley   +1 more source

Ascorbate peroxidase modulation confirms key role in Leishmania infantum oxidative defence

open access: yesParasites & Vectors
Background Ascorbate peroxidase (APX) has emerged as a promising target for chemotherapy because of its absence in humans and crucial role in the antioxidant defence of trypanosomatids.
Isabella Fernandes Martins Santos   +5 more
doaj   +1 more source

Visualising iron gall ink underdrawings in sixteenth century paintings in-situ by micro-XRF scanning (MA-XRF) and LED-excited IRR (LEDE-IRR)

open access: yesHeritage Science, 2022
Until today, iron gall ink is classified as an exceptional underdrawing material for paintings. Its study and definite identification is usually based on invasive analysis.
Mareike Gerken   +2 more
doaj   +1 more source

PENERAPAN METODE DSS (MAUT & IRR) DALAM MENENTUKAN KELAYAKAN PENGADUAN

open access: yesSINTECH (Science and Information Technology) Journal, 2022
The research and development center for mineral and coal technology or abbreviated as Puslitbang tekMIRA is located in Bandung, West Java, which has asset management, namely the rental of rooms or buildings. In asset management, there is a complaint page
Andi Nurfadillah Ali, Khaera Tunnisa
doaj   +1 more source

An Agonist/Antagonist Photo‐Switchable Vitamin D Mimetic Enables Bidirectional Optical Control of VDR

open access: yesAngewandte Chemie International Edition, EarlyView.
Vitamin D exhibits complex and cell‐specific biological effects in multiple tissues via activation of the ligand‐sensing transcription factor vitamin D receptor (VDR). The photo‐switchable vitamin D mimetic 10 transitions between VDR antagonist (E) and agonist (Z) activity upon illumination and offers unprecedented bidirectional optical control over ...
Xiu Ge   +11 more
wiley   +1 more source

Most Upper Extremity Injuries in Elite Summer League Baseball Players Occur From Overuse, Affect the Shoulder, and Result in Missed Playing Time

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To characterize the epidemiology of upper extremity injuries among elite college baseball players in 1 league over 5 seasons. Methods Deidentified arm injury reports were recorded from the 2018, 2019, 2021, 2022, and 2023 Cape Cod Baseball League (CCBL) seasons.
David F. Painter   +6 more
wiley   +1 more source

Presenting a mathematical approach to developing the internal rate of Return method: An application of Horner's theorem in econometrics [PDF]

open access: yesMathematics and Computational Sciences
Economics is the development of a collection of Mathematical Methods(MMs) for the economic evaluation of investment projects or plans. Two main methods for this type of valuation are the internal rate of return method and the present value method.
Hossein Jafari   +2 more
doaj   +1 more source

Equivalence Analysis of LCOE and IRR for New Energy Projects

open access: yes南方能源建设, 2023
[Introduction] With the development of domestic renewable energy industry, the recession of governmental subsidies and the implementation of policies such as competitive allocation of resources, Levelized Cost of Energy (LCOE) is gaining more and more ...
Dongjie WANG, Binsi LI, Sikai ZHOU
doaj   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló   +5 more
wiley   +1 more source

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

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