Results 71 to 80 of about 1,224,659 (295)
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Preparation process and performance of graphene oxide-doped UO2 pellets
BackgroundUranium dioxide (UO2) has been broadly employed as nuclear fuel in nuclear reactors. However, the poor thermal conductivity of UO2 compromises the safety of the reactor owing to possible sharp temperature gradients.
WEN Feng +6 more
doaj +1 more source
World Market Development and Consumer Acceptance of Irradiation Technology
Food irradiation is an efficient technology that can be used to ensure food safety by eliminating insects and pathogens to prolong the shelf life. The process could be applied to fresh or frozen products without affecting the nutritional value. Presently
Behnoush Maherani +5 more
doaj +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Probing the linear polarization of photons in ultraperipheral heavy ion collisions
We propose to measure the linear polarization of the external electromagnetic fields of a relativistic heavy ion through azimuthal asymmetries in dilepton production in ultraperipheral collisions.
Cong Li, Jian Zhou, Ya-jin Zhou
doaj +1 more source
Proton irradiation of simple gas mixtures: Influence of irradiation parameters [PDF]
In order to get information about the influence of irradiation parameters on radiolysis processes of astrophysical interest, methane gas targets were irradiated with 6.5 MeV protons at a pressure of 1 bar and room temperature.
Hofmann, A. +2 more
core +1 more source
Black-Hole X-Ray Transients: The Effect of Irradiation on Time-Dependent Accretion Disk Structure
Some effects of irradiation on time-dependent accretion-disk models for black hole X-ray novae are presented. Two types of irradiation are considered: direct irradiation from the inner hot disk and indirect irradiation as might be reflected by a corona ...
Kim, Soon-Wook +2 more
core +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source

