Results 41 to 50 of about 5,873 (297)
Effect of Au-ions irradiation on microstructure and mechanical properties of FeCrAl coating
Journal of Materials Research and Technology, 2023 Six kinds of FeCrAl coatings with different Cr and Al contents were irradiated by 6 MeV Au-ions with a damage level of 20 dpa. The results showed that the surface roughness and grain size of the coatings increased significantly after irradiation ...
Wei Zhang +7 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Simulation of the irradiation effect on hardness of Chinese HTGR A508-3 steels with CPFEM
Nuclear Engineering and Technology, 2019 Understanding the irradiation hardening effect of structural steels under various irradiation conditions plays an important role in developing advanced nuclear systems. Such being the case, a crystal plasticity model for body-centered cubic (BCC) crystal
Junfeng Nie +4 more
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Journal of Materials Research and TechnologyThe weld cladding on the inner surface of nuclear pressure vessels due to irradiation damage and thermal effect presents to a safety issue. Unfortunately, the effect of irradiation and long-term thermal treatment on the austenitic microstructure and ...
Xiaodong Gao +5 more
doaj +1 more source
Irradiation-induced precipitation modelling of ferritic steels [PDF]
, 2009 In high strength low alloy (HSLA) steels typically used in reactor pressure vessels (RPV), irradiation-induced microstructure changes affect the performance of the components.
Youfa Yin (1248846) +2 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Irradiation-Induced Hardening of Structural Materials after Low Temperature Irradiation [PDF]
, 2019 Секция 2. Радиационные эффекты в твердом теле = Section 2. Radiation Effects in SolidsIrradiation-induced hardening has been investigated in relation to austenitic SS316 steel, ferritic-martensitic T91 steel and 20Cr-40Fe-20Mn-20Ni high-entropy alloy ...
Tolstolutskaya, G. D., Karpov, S. A.
core +2 more sources
Nuclear Materials and Energy, 2023 This work investigates the irradiation hardening and deuterium (D) retention behaviour of tungsten (W) under synergistic irradiations of heavy ions and D plasma.
Ting Wang +9 more
doaj +1 more source
Effect of recrystallization on ion-irradiation hardening and microstructural changes in 15Cr-ODS steel [PDF]
, 2015 Proceedings of the 19th International Conference on Ion Beam Modification of Materials (IBMM 2014)The effects of recrystallization on ion-irradiation hardening and microstructural changes were investigated for a 15Cr-ODS ferritic steel.
Ha, Yoosung, Kimura, Akihiko
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