Results 61 to 70 of about 467,366 (245)

Studies on the correlation between irradiation hardening and thermal conductivity of RPV steel irradiated with protons

Journal of Materials Research and Technology
Reactor pressure vessel (RPV) is a critical safety component in nuclear power plants, and irradiation embrittlement induced by hardening is its primary safety challenge.
Chaoliang Xu, Wenqing Jia, Qiwei Quan, Yuanfei Li, Jian Yin, Huanchun Wu, Xiao Jin, Xianglong Guo, Xiangbing Liu   +8 more
doaj   +1 more source

Effect of Strengthening Methods on the Defect Evolution under Irradiations Investigated with Rate Theory Simulations

Metals, 2019
Under irradiations, mechanical performance of nuclear alloys would degrade due to irradiation induced defects. Different strengthening methods can play a different role in the evolution of the defects.
Cheng Chen, Liping Guo, Yaxia Wei, Ziyang Xie, Yunxiang Long   +4 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

A multiscale study on the microstructure and hardening models of the irradiation defects on reactor pressure vessel steels: Modelling and experiment

Journal of Materials Research and Technology
Irradiation defects are known to impede the dislocation motion in irradiated reactor pressure vessel (RPV) steels. However, consistent experimental studies of the respective irradiation defects and relevant theoretical studies of the interaction ...
Pan-dong Lin, Jun-feng Nie, Wen-dong Cui, Lei He, Yu-peng Lu, Shu-gang Cui   +5 more
doaj   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Effects of helium production, displacement damage on mechanical properties and surface acoustic wave in austenitic stainless steels and martensitic steel

Nuclear Materials and Energy, 2018
The effects of helium production, displacement damage on mechanical properties and microstructures were investigated in some specimens such as austenitic stainless steels of SUS304 and SUS316 and a high chromium martensitic steel of HCM12A steels ...
E. Wakai, S. Kitazawa, S. Takaya, N. Okubo, Y. Nagae, T. Iwai, T. Omata, H. Abe, K. Aoto   +8 more
doaj   +1 more source

Effect of recrystallization on ion-irradiation hardening and microstructural changes in 15Cr-ODS steel [PDF]

, 2015
Proceedings of the 19th International Conference on Ion Beam Modification of Materials (IBMM 2014)The effects of recrystallization on ion-irradiation hardening and microstructural changes were investigated for a 15Cr-ODS ferritic steel.
Ha, Yoosung, Kimura, Akihiko
core   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Microstructural changes in He-irradiated V-Cr-Ti alloys with low Ti addition at 700 °C

Nuclear Materials and Energy
V-Cr-Ti alloys with reduced Ti contents are expected to be good candidates as recyclable structural materials for fusion reactors. Herein, He irradiation was applied to V-4Cr-xTi (x = 0 to 4) alloys to investigate the additional effect of Ti and gas ...
Yichen Zou, Ken-ichi Fukumoto, Ryoya Ishigami, Takuya Nagasaka   +3 more
doaj   +1 more source