Results 51 to 60 of about 467,366 (245)

Proton and Au-ion irradiation induced damage and hardening in ferritic/martensitic steel

Nuclear Materials and Energy, 2021
Ferritic/martensitic (F/M) steel was irradiated by proton and Au-ion at 400 °C to investigate the irradiation damage and hardening behavior. For the samples irradiated by proton, dislocation loops and dislocation lines were found in F/M steels and the ...
Ke Shi, Wei Zhang, Zhien Ning, Hui Wang, Jiali Liao, Yuanyou Yang, Ning Liu, Jijun Yang   +7 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Machine learning predictions of irradiation embrittlement in reactor pressure vessel steels

npj Computational Materials, 2022
Irradiation increases the yield stress and embrittles light water reactor (LWR) pressure vessel steels. In this study, we demonstrate some of the potential benefits and risks of using machine learning models to predict irradiation hardening extrapolated ...
Yu-chen Liu, Henry Wu, Tam Mayeshiba, Benjamin Afflerbach, Ryan Jacobs, Josh Perry, Jerit George, Josh Cordell, Jinyu Xia, Hao Yuan, Aren Lorenson, Haotian Wu, Matthew Parker, Fenil Doshi, Alexander Politowicz, Linda Xiao, Dane Morgan, Peter Wells, Nathan Almirall, Takuya Yamamoto, G. Robert Odette   +20 more
doaj   +1 more source

Transmission electron microscopy with in situ ion irradiation [PDF]

, 2015
The macroscopic properties of materials exposed to irradiation are determined by radiation damage effects which occur on the nanoscale. These phenomena are complex dynamic processes in which many competing mechanisms contribute to the evolution of the ...
Hinks, Jonathan Andrew, Hinks, J. A.
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Evaluation of irradiation hardening of ion-irradiated V–4Cr–4Ti and V–4Cr–4Ti–0.15Y alloys by nanoindentation techniques [PDF]

, 2014
0000-0001-6564-8922Irradiation hardening behavior of V–4Cr–4Ti and V–4Cr–4Ti–0.15Y alloys after Cu-ion beam irradiation were investigated with a combination between nanoindentation techniques and finite element method (FEM) analysis.
HISHINUMA, Yoshimitsu, WATANABE, Hideo, NOGAMI, Shuhei, YAMAMOTO, Takuya, NAGASAKA, Takuya, MUROGA, Takeo, HATAKEYAMA, Masahiko, MIYAZAWA, Takeshi, KASADA, Ryuta   +8 more
core   +3 more sources

Effect of high energy helium ion irradiation on microstructure and mechanical response of CLAM steel

Cailiao gongcheng
The blanket structural material of fusion reactor will induce radiation damage during the period of service. As the preferred structural material of thermonuclear fusion reactor, it is necessary to study its radiation behaviour.
LUO Aibo, LIANG Yanxiang, YAO Yong, WANG Luobin, WAN Qiang   +4 more
doaj   +1 more source

Hardening and Creep of Ion Irradiated CLAM Steel by Nanoindentation

Crystals, 2020
Ion irradiation, combined with nanoindentation, has long been recognized as an effective way to study effects of irradiation on the mechanical properties of metallic materials.
Ying Liu, Wenbin Liu, Long Yu, Lirong Chen, Haonan Sui, Huiling Duan   +5 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source