Results 71 to 80 of about 16,816 (261)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Fourth Order Diffusion Equations with Increasing Entropy

open access: yesEntropy, 2012
The   general   quasi-linear  autonomous  fourth   order   diffusion   equation <em>u<sub>t</sub> = −[G(u)u<sub>xxx </sub> + h(u, u<sub>x</sub>, u<sub>xx</sub>)]<sub>x </sub></em> ...
Philip Broadbridge, Naghmana Tehseen
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Nonequilibrium and Irreversibility

open access: yes, 2013
The work concentrates on relations, which are general and model independent in chaotic system, between time averages of a few (typically {\it very few}) observables. Equilibrium thermodynamics provides a guide and here is attempted to argue that the viewpoint of Sinai-Ruelle-Bowen can be regarded as a generalization to nonequilibrum phenomena of the ...
openaire   +3 more sources

Irreversibility of Entanglement Loss [PDF]

open access: yes, 2008
14 pages, 3 figures, llncs.sty; contribution to the proceedings of TQC2008, Tokyo. Few typos corrected. To appear in: [Y. Kawano and M. Mosca (eds.): TQC 2008, LNCS 5106, pp.16-28, 2008]
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Historicidad e irreversibilidad en la concepción prigoginiana y agustiniana del tiempo

open access: yesTópicos, 2003
El trabajo compara las nociones de "historicidad" e "irreversibilidad" en la concepción del tiempo de Prigogine y de San Agustín, estableciendo semejanzas y diferencias.
Eduardo Ibáñez
doaj  

Entropy, Extropy and the Physical Driver of Irreversibility [PDF]

open access: yesInterdisciplinary Description of Complex Systems, 2012
We point out that the fundamental irreversibility of Nature requires the introduction of a suitable measure for the distance from equilibrium. We show that entropy, which is widely held to be such a measure, suffers from the problem that it does not have
Attila Grandpierre
doaj  

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