Results 81 to 90 of about 35,904 (298)

Investment, irreversibility and financial imperfections: the rush to invest and the option to wait [PDF]

open access: yes
The impact of combinations of frictions on investment activity is poorly understood. We develop a model of investment under financial frictions and irreversibility.
Richard Holt
core  

Fourth Order Diffusion Equations with Increasing Entropy

open access: yesEntropy, 2012
The   general   quasi-linear  autonomous  fourth   order   diffusion   equation <em>u<sub>t</sub> = −[G(u)u<sub>xxx </sub> + h(u, u<sub>x</sub>, u<sub>xx</sub>)]<sub>x </sub></em> ...
Philip Broadbridge, Naghmana Tehseen
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Optimal Preservation of Agricultural and Environmental Land within a Municipality Under Irreversibility and Uncertainty [PDF]

open access: yes
Replaced with revised version of paper 07/22/11.Uncertainty, Irreversibility, Spatial-temporal modeling, Value of information, Policy design, Climate change, Agricultural preservation, Environmental conservation, Environmental Economics and Policy, Land ...
Howard, Peter H.
core  

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto   +12 more
wiley   +1 more source

Irreversibility of Entanglement Loss [PDF]

open access: yes, 2008
14 pages, 3 figures, llncs.sty; contribution to the proceedings of TQC2008, Tokyo. Few typos corrected. To appear in: [Y. Kawano and M. Mosca (eds.): TQC 2008, LNCS 5106, pp.16-28, 2008]
openaire   +3 more sources

Molecular theory of irreversibility [PDF]

open access: yesThe Journal of Chemical Physics, 2005
A generalization of the Gibbs entropy postulate is proposed based on the Bogolyubov-Born-Green-Kirkwood-Yvon hierarchy of equations as the nonequilibrium entropy for a system of N interacting particles. This entropy satisfies the basic principles of thermodynamics in the sense that it reaches its maximum at equilibrium and is coherent with the second ...
openaire   +3 more sources

Investment, Irreversibility, and Financial Imperfections [PDF]

open access: yes
Research finds that firms' investment decisions are distorted by irreversibility and finance constraints. Whereas the existing literature examines the exects of these features separately, this paper studies their interaction.
Richard Holt
core  

cjoshliu/irreversibility-from-representations: Pre-publication code for "Measuring irreversibility from learned representations of biological patterns"

open access: yes
<p>Code for "Measuring irreversibility from learned representations of biological patterns"</p ...
Josh Liu
core   +1 more source

Home - About - Disclaimer - Privacy