Results 81 to 90 of about 35,904 (298)
Investment, irreversibility and financial imperfections: the rush to invest and the option to wait [PDF]
The impact of combinations of frictions on investment activity is poorly understood. We develop a model of investment under financial frictions and irreversibility.
Richard Holt
core
Fourth Order Diffusion Equations with Increasing Entropy
The general quasi-linear autonomous fourth order diffusion equation <em>u<sub>t</sub> = −[G(u)u<sub>xxx </sub> + h(u, u<sub>x</sub>, u<sub>xx</sub>)]<sub>x </sub></em> ...
Philip Broadbridge, Naghmana Tehseen
doaj +1 more source
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Optimal Preservation of Agricultural and Environmental Land within a Municipality Under Irreversibility and Uncertainty [PDF]
Replaced with revised version of paper 07/22/11.Uncertainty, Irreversibility, Spatial-temporal modeling, Value of information, Policy design, Climate change, Agricultural preservation, Environmental conservation, Environmental Economics and Policy, Land ...
Howard, Peter H.
core
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto +12 more
wiley +1 more source
Irreversibility of Entanglement Loss [PDF]
14 pages, 3 figures, llncs.sty; contribution to the proceedings of TQC2008, Tokyo. Few typos corrected. To appear in: [Y. Kawano and M. Mosca (eds.): TQC 2008, LNCS 5106, pp.16-28, 2008]
openaire +3 more sources
Molecular theory of irreversibility [PDF]
A generalization of the Gibbs entropy postulate is proposed based on the Bogolyubov-Born-Green-Kirkwood-Yvon hierarchy of equations as the nonequilibrium entropy for a system of N interacting particles. This entropy satisfies the basic principles of thermodynamics in the sense that it reaches its maximum at equilibrium and is coherent with the second ...
openaire +3 more sources
Investment, Irreversibility, and Financial Imperfections [PDF]
Research finds that firms' investment decisions are distorted by irreversibility and finance constraints. Whereas the existing literature examines the exects of these features separately, this paper studies their interaction.
Richard Holt
core
<p>Code for "Measuring irreversibility from learned representations of biological patterns"</p ...
Josh Liu
core +1 more source

